Evidence map›Paper›PMID 39432032›Full record

ArticleMedical physics2025

Motion and anatomy dual aware lung ventilation imaging by integrating Jacobian map and average CT image using dual path fusion network.

Pei Ma, Zhi Chen, Yu-Hua Huang, Mayang Zhao, Wen Li, Haojiang Li, Di Cao, Yi-Quan Jiang, Ta Zhou, Jing Cai and 1 more

Abstract read
In one paragraph

Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Research progress on predicting radiation pneumonia based on four-dimensional computed tomography ventilation imaging in lung cancer radiotherapy].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Pei MaDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, Hong Kong.
Zhi ChenDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, Hong Kong.
Yu-Hua HuangDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, Hong Kong.
Mayang ZhaoDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, Hong Kong.
Wen LiDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, Hong Kong.
Haojiang LiDepartment of Radiology, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Centre, Guangzhou, People's Republic of China.
Di CaoDepartment of Radiology, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Centre, Guangzhou, People's Republic of China.
Yi-Quan JiangDepartment of Minimally Invasive Interventional Therapy, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
Ta ZhouDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, Hong Kong.
Jing CaiDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, Hong Kong.
Ge RenDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, Hong Kong.

Funding

Health and Medical Research Fund 09200576Health Bureau, the Pneumoconiosis Compensation Fund Board in HKSAR, and Shenzhen Science and Technology Program JCYJ20230807140403007the Shenzhen Basic Research Program JCYJ20210324130209023
6 · The paper itself

Abstract

backgroundDeep learning-based computed tomography (CT) ventilation imaging (CTVI) is a promising technique for guiding functional lung avoidance radiotherapy (FLART). However, conventional approaches, which rely on anatomical CT data, may overlook important ventilation features due to the lack of motion data integration. PURPOSE: This study aims to develop a novel dual-aware CTVI method that integrates both anatomical information from CT images and motional information from Jacobian maps to generate more accurate ventilation images for FLART.

methodsA dataset of 66 patients with four-dimensional CT (4DCT) images and reference ventilation images (RefVI) was utilized to develop the dual-path fusion network (DPFN) for synthesizing ventilation images (CTVI

resultsIn the test group, the mean R between CTVI

conclusionsA novel dual-aware CTVI model that integrates anatomical and motion information was developed to synthesize lung ventilation images. It was shown that the accuracy of lung ventilation estimation could be significantly enhanced by incorporating motional information, particularly in patients with tumor-induced blockages. This approach has the potential to improve the accuracy of CTVI, enabling more effective FLART.

Indexed as

Four-Dimensional Computed TomographyImage Processing, Computer-AssistedLungDeep LearningHumansLung NeoplasmsMovementPulmonary VentilationRespirationCT ventilation imagingdeep learningfunctional lung avoidance radiotherapyJacobian map

Identifiers

PMID39432032
PMCPMC11700001

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.