Evidence map›Paper›PMID 39431820›Full record

ReviewJournal of virology2024

Comprehensive phage display viral antibody profiling using VirScan: potential applications in chronic immune-mediated disease.

Jed Valentiner Shrewsbury, Evangelin Shaloom Vitus, Adam Leslie Koziol, Anna Nenarokova, Tine Jess, Rahma Elmahdi

Abstract readReview
In one paragraph

Review in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. A Genome-Wide Screening of Novel Immunogenic TrLSDV103 Protein of Lumpy Skin Disease Virus and Its Application for DIVA.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jed Valentiner ShrewsburyFaculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0003-0604-6467
Evangelin Shaloom VitusCentre for Molecular Prediction of Inflammatory Bowel Disease (PREDICT), Department of Clinical Medicine, Aalborg University, Copenhagen, Denmark.
Adam Leslie KoziolCentre for Molecular Prediction of Inflammatory Bowel Disease (PREDICT), Department of Clinical Medicine, Aalborg University, Copenhagen, Denmark.ORCID 0000-0002-7721-4790
Anna NenarokovaPrivate researcher, London, United Kingdom.ORCID 0000-0003-1441-037X
Tine JessCentre for Molecular Prediction of Inflammatory Bowel Disease (PREDICT), Department of Clinical Medicine, Aalborg University, Copenhagen, Denmark.ORCID 0000-0002-4391-7332
Rahma ElmahdiCentre for Molecular Prediction of Inflammatory Bowel Disease (PREDICT), Department of Clinical Medicine, Aalborg University, Copenhagen, Denmark.ORCID 0000-0002-7013-9548

Funding

Danish National Research Foundation DNRF-148Linder FoundationLundbeck Foundation (Lundbeckfonden) R403-2022-1531Novo Nordisk Foundation NNF21OC0068631Turing Scheme
6 · The paper itself

Abstract

Phage immunoprecipitation sequencing (PhIP-Seq) is a high-throughput platform that uses programmable phage display for serology. VirScan, a specific PhIP-Seq library encoding viral peptides from all known human viruses, enables comprehensive quantification of past viral exposures. We review its use in immune-mediated diseases (IMDs), highlighting its utility in identifying viral exposures in the context of IMD development. Finally, we evaluate its potential for precision medicine by integrating it with other large-scale omics data sets.

Indexed as

Antibodies, ViralCell Surface Display TechniquesPeptide LibraryChronic DiseaseHigh-Throughput Nucleotide SequencingHumansImmune System DiseasesImmunoprecipitationVirusesAntibodies, ViralPeptide Libraryimmune-mediated diseasephage immunoprecipitation sequencingPhIP-SeqVirScanviruses

Identifiers

PMID39431820
PMCPMC11575288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.