Evidence map›Paper›PMID 39431551›Full record

ArticleJournal of cellular and molecular medicine2024

JAK2V617F-dependent down regulation of SHP-1 expression participates in the selection of myeloproliferative neoplasm cells in the presence of TGF-β.

Céline Aoun, Nabih Maslah, Saravanan Ganesan, Norman Salomao, Romane Gendron, Sarah Awan Toor, Gil Letort, Panhong Gou, Mélina Bonnamy, Véronique Parietti and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Céline AounInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Nabih MaslahInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Saravanan GanesanInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Norman SalomaoInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Romane GendronInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Sarah Awan ToorInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Gil LetortInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Panhong GouInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Mélina BonnamyInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Véronique PariettiUniversité Paris Cité, INSERM/CNRS, US53/UAR2030, Institut de Recherche Saint-Louis, Paris, France.
Jean-Jacques KiladjianInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Stephane GiraudierInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Bruno CassinatInserm UMRS_1131, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.ORCID 0000-0002-6514-3905

Funding

Fondation ARC pour la Recherche sur le CancerFondation Leucemie EspoirInstitut National Du Cancer INCa Prev-Bio 2021
6 · The paper itself

Abstract

Myeloproliferative neoplasms (MPNs) are characterized by an increased production of blood cells due to the acquisition of mutations such as JAK2

Indexed as

Cell ProliferationJanus Kinase 2Myeloproliferative DisordersProtein Tyrosine Phosphatase, Non-Receptor Type 6Transforming Growth Factor betaAnimalsCell Line, TumorDown-RegulationHematopoietic Stem CellsHumansMiceMutationPhosphorylationSmad2 ProteinJAK2 protein, humanJanus Kinase 2Protein Tyrosine Phosphatase, Non-Receptor Type 6Smad2 ProteinTransforming Growth Factor betaJAK2Myeloproliferative neoplasmsSHP‐1TGF‐β

Identifiers

PMID39431551
PMCPMC11492149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.