Evidence map›Paper›PMID 39431526›Full record

ArticlePhotochemistry and photobiology

Extending the acute skin response spectrum to include the far-UVC.

Natalia E Gutierrez-Bayona, Camryn Petersen, Raabia H Hashmi, Manuela Buonanno, Igor Shuryak, Brian Ponnaiya, Norman J Kleiman, David J Brenner, David Welch

Abstract read
In one paragraph

Article in Photochemistry and photobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Natalia E Gutierrez-BayonaCenter for Radiological Research, Columbia University Irving Medical Center, New York City, New York, USA.ORCID 0009-0000-8945-8912
Camryn PetersenCenter for Radiological Research, Columbia University Irving Medical Center, New York City, New York, USA.
Raabia H HashmiCenter for Radiological Research, Columbia University Irving Medical Center, New York City, New York, USA.
Manuela BuonannoCenter for Radiological Research, Columbia University Irving Medical Center, New York City, New York, USA.ORCID 0000-0002-3455-3602
Igor ShuryakCenter for Radiological Research, Columbia University Irving Medical Center, New York City, New York, USA.
Brian PonnaiyaCenter for Radiological Research, Columbia University Irving Medical Center, New York City, New York, USA.
Norman J KleimanDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University Irving Medical Center, New York City, New York, USA.
David J BrennerCenter for Radiological Research, Columbia University Irving Medical Center, New York City, New York, USA.
David WelchCenter for Radiological Research, Columbia University Irving Medical Center, New York City, New York, USA.ORCID 0000-0003-2784-496X

Funding

Testing health hazards from implementation of far-UVC irradiation as an intervention technology to reduce airborne disease transmissionR01OH012312 · OH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WELCH, DAVID · 2022 to 2025
$2.6M
NIOSH CDC HHS R01 OH012312NIOSH CDC HHS R01OH012312
6 · The paper itself

Abstract

Guidance on maximal limits for ultraviolet (UV) exposure has been developed by national and international organizations to protect against adverse effects on human skin and eyes. These guidelines consider the risk of both acute effects (i.e., erythema and photokeratitis) and delayed effects (e.g., skin and ocular cancers) when determining exposure limits, and specify the dose a person can safely receive during an 8-h period without harmful effects. The determination of these exposure limits relies on the action spectra of photobiological responses triggered by UV radiation that quantify the effectiveness of each wavelength at eliciting each of these effects. With growing interest in using far-UVC (200-235 nm) radiation to control the spread of airborne pathogens, recent arguments have emerged about revisiting exposure limits for UV wavelengths. However, the standard erythema action spectrum, which provides some of the quantitative basis for these limits, has not been extended below 240 nm. This study assists to expand the erythema action spectrum to far-UVC wavelengths using a hairless albino mice model. We estimate that inducing acute effects on mouse skin with 222 nm radiation requires a dose of 1162 mJ/cm

Indexed as

SkinUltraviolet RaysAnimalsErythemaHumansMiceMice, Hairlessacute effectsfar‐UVCskin safety

Identifiers

PMID39431526
PMCPMC12019814

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.