Evidence map›Paper›PMID 39430794›Full record

ArticleClinical kidney journal2024

Modified creatinine index as a marker of skeletal muscle mass in peritoneal dialysis patients.

Jack Kit-Chung Ng, Winston Wing-Shing Fung, Gordon Chun-Kau Chan, Phyllis Mei-Shan Cheng, Wing-Fai Pang, Kai-Ming Chow, Cheuk-Chun Szeto

Abstract read
In one paragraph

Article in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jack Kit-Chung NgCarol & Richard Yu Peritoneal Dialysis Research Centre, Departments of Medicine & Therapeutics, Prince of Wales Hospital.
Winston Wing-Shing FungCarol & Richard Yu Peritoneal Dialysis Research Centre, Departments of Medicine & Therapeutics, Prince of Wales Hospital.ORCID https://orcid.org/0000-0001-7676-7628
Gordon Chun-Kau ChanCarol & Richard Yu Peritoneal Dialysis Research Centre, Departments of Medicine & Therapeutics, Prince of Wales Hospital.ORCID https://orcid.org/0000-0003-4681-7326
Phyllis Mei-Shan ChengCarol & Richard Yu Peritoneal Dialysis Research Centre, Departments of Medicine & Therapeutics, Prince of Wales Hospital.
Wing-Fai PangCarol & Richard Yu Peritoneal Dialysis Research Centre, Departments of Medicine & Therapeutics, Prince of Wales Hospital.
Kai-Ming ChowCarol & Richard Yu Peritoneal Dialysis Research Centre, Departments of Medicine & Therapeutics, Prince of Wales Hospital.
Cheuk-Chun SzetoCarol & Richard Yu Peritoneal Dialysis Research Centre, Departments of Medicine & Therapeutics, Prince of Wales Hospital.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sarcopenia is common in peritoneal dialysis (PD) patients. Modified creatinine index (MCrI) by the Canaud's formula and single-pool Kt/V value is an accurate surrogate marker for muscle mass in hemodialysis patients. However, the method of calculation and validity of MCrI has not been tested in PD. Methods: In the exploratory cohort, we studied 138 consecutive patients converted from PD to hemodialysis. Their MCrI during PD, calculated by the Canaud's formula with total weekly Kt/V, and the conventional MCrI after conversion to HD, were compared by the Bland-Altman method. Their correlation with muscle mass as determined by bioimpedance spectroscopy and creatinine kinetic methods was explored. The result was then validated in a second cohort of 605 incident PD patients. Results: In the exploratory cohort, the average bias of computing MCrI during PD and hemodialysis was 0.758 mg/kg/day (95%CI -4.356 to 5.873 mg/kg/day). The MCrI during PD significantly correlated with the muscle mass by creatinine kinetics ( Conclusion: In PD patients, MCrI computed by the Canaud's formula and total weekly Kt/V is a simple and reliable marker of skeletal muscle mass and may serve as a short-term prognostic indicator.

Indexed as

frailtymalnutritionrenal failure

Identifiers

PMID39430794
PMCPMC11487157

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.