Evidence map›Paper›PMID 39430351›Full record

ArticleTaiwan journal of ophthalmology

Comparison of changes in number of hyperreflective dots after intravitreal ranibizumab or dexamethasone implant in patients with branch retinal vein occlusion.

Aylin Karalezli, Sema Tamer Kaderli, Ahmet Kaderli, Cansu Kaya, Sabahattin Sul

Abstract read
In one paragraph

Article in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aylin KaralezliDepartment of Ophthalmology, Mugla Sitki Kocman University School of Medicine, Mugla, Turkey.
Sema Tamer KaderliDepartment of Ophthalmology, Mugla Sitki Kocman Education and Training Hospital, Mugla, Turkey.
Ahmet KaderliDepartment of Ophthalmology, Mugla Sitki Kocman University School of Medicine, Mugla, Turkey.
Cansu KayaDepartment of Ophthalmology, Mugla Sitki Kocman University School of Medicine, Mugla, Turkey.
Sabahattin SulDepartment of Ophthalmology, Mugla Sitki Kocman University School of Medicine, Mugla, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the effect of intravitreal ranibizumab (IVR) or intravitreal dexamethasone implants (IVD) on the regression of hyperreflective dots (HRDs) in patients with branch retinal vein occlusion (BRVO). MATERIALS AND

methodsThirty-seven eyes with cystoid macular edema who received IVR or IVD and followed up for at least 12 months were included in this study. The patients were divided into three Groups according to intravitreal treatments. Group 1 consisted of 12 eyes who received only IVD, Group 2 consisted of 10 eyes who received only IVR, and Group 3 consisted of 15 eyes who received both IVD and IVR. The number of HRDs and best-corrected visual acuity (BCVA) were compared between the Groups through the follow-up time.

resultsThe mean number of HRDs in inner and outer retinal layers was significantly decreased in Group 1 and Group 3 (For Group 1;

conclusionThe HRDs should be considered inflammatory markers in the follow-up of CME in BRVO.

Indexed as

Branch retinal vein occlusionhyperreflective dotsintravitreal dexamethasoneintravitreal ranibizumaboptic coherence tomography

Identifiers

PMID39430351
PMCPMC11488816

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.