Evidence map›Paper›PMID 39430343›Full record

ArticleExperimental and therapeutic medicine2024

Peimine induces apoptosis of glioblastoma cells through regulation of the PI3K/AKT signaling pathway.

Jiaming Lei, Jianbao Yang, Shijiao Cheng, Feifei Lu, Zihan Wu, Ziyi Wang, Ziqi Wang, Chenyu Sun, Li Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiaming LeiSchool of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Jianbao YangSchool of Public Health, Xianning Medical College, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Shijiao ChengSchool of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Feifei LuSchool of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Zihan WuDepartment of Ultrasound, Xianning Traditional Chinese Medicine Hospital, Xianning, Hubei 437100, P.R. China.
Ziyi WangDepartment of Medicine, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Ziqi WangDepartment of Medicine, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Chenyu SunDepartment of Medicine, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Li LinKey Laboratory of Environmental Related Diseases and One Health, School of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is one of the most malignant forms of intracranial tumors, with high mortality rates and invariably poor prognosis, due to the limited clinical treatment strategies available. As a natural compound, peimine's favorable pharmacological activities have been widely revealed. However, potential inhibitory effects of peimine on GBM have not been explored. In the present study, both

Indexed as

apoptosisglioblastomapeiminePI3K/AKTproliferation

Identifiers

PMID39430343
PMCPMC11487465

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.