Evidence map›Paper›PMID 39430250›Full record

ArticleInternational journal of biological sciences2024

NUSAP1 is Upregulated by Estrogen to Promote Lung Adenocarcinoma Growth and Serves as a Therapeutic Target.

Shaoping Zhang, Xiaozhen Zhang, Wenjian Huang, Ganling Jiang, Yuanxin Mo, Liuxia Wei, Pingming Fan, Maojian Chen, Wei Jiang

Abstract read
In one paragraph

Article in International journal of biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The role and therapeutic value of NUSAP1 in human cancers.Journal of translational medicine · 2025
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shaoping ZhangDepartment of Respiratory Oncology, Guangxi Medical University Cancer Hospital, Nanning 530021, China.
Xiaozhen ZhangDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning 530021, China.
Wenjian HuangDepartment of Breast Surgery, the Sixth Affiliated Hospital of South China University of Technology, the Sixth Clinical College of South China University of Technology, Foshan 528225, China.
Ganling JiangDepartment of pharmacy, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510145, China.
Yuanxin MoDepartment of Respiratory Oncology, Guangxi Medical University Cancer Hospital, Nanning 530021, China.
Liuxia WeiDepartment of Medical Oncology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530000, China.
Pingming FanDepartment of Breast Surgery, the First Affiliated Hospital of Hainan Medical University, Haikou 570102, Hainan, China.
Maojian ChenDepartment of Respiratory Oncology, Guangxi Medical University Cancer Hospital, Nanning 530021, China.
Wei JiangDepartment of Respiratory Oncology, Guangxi Medical University Cancer Hospital, Nanning 530021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nucleolar and spindle-associated protein 1 (NUSAP1), a microtubule-associated protein, has been recently identified to exhibit aberrant expression patterns that correlate with malignant tumorigenesis and progression across various cancer types. However, the specific regulatory mechanisms and potential targeting therapies of NUSAP1 in lung adenocarcinoma (LUAD) remain largely elusive. In this study, by conducting bioinformatics analyses as well as

Indexed as

AdenocarcinomaAntineoplastic AgentsEstrogen Receptor betaLung NeoplasmsMicrotubule-Associated ProteinsA549 CellsAnimalsBenzamidesDrug Screening Assays, AntitumorEstradiolEstrogen Receptor AntagonistsFemaleFulvestrantHEK293 CellsHumansImmune Checkpoint InhibitorsAntineoplastic AgentsBenzamidesentinostatEstradiolEstrogen Receptor AntagonistsEstrogen Receptor betaFulvestrantImmune Checkpoint InhibitorsMicrotubule-Associated ProteinsNUSAP1 protein, humanPyridinesentinostatestrogenfulvestrantlung adenocarcinomanucleolar and spindle-associated protein 1

Identifiers

PMID39430250
PMCPMC11489181

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.