Evidence map›Paper›PMID 39430177›Full record

ArticleKidney international reports2024

Stepped-Wedge Trial of Decision Support for Acute Kidney Injury on Surgical Units.

Matthew T James, Elijah Dixon, Zhi Tan, Pamela Mathura, Indraneel Datta, Rohan N Lall, Jennifer Landry, Evan P Minty, Gregory A Samis, Gerald B Winkelaar and 1 more

Registry-linked trialAbstract read
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In one paragraph

Article in Kidney international reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07604662 (Prediction of Acute Kidney Injury), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07604662 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Prediction of Acute Kidney Injury (AKI) After Surgery: A Pragmatic Three-Arm Cluster-Randomized Trial

TypeinterventionalSponsorUniversity of California, San FranciscoRan2026 to 2027Enrolled25,518ConditionsAcute Kidney Injury, Surgery Complications, AnesthesiaArmsEHR-Embedded AKI Risk Score, EHR-Embedded AKI Risk Score with Best Practice Advisory
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matthew T JamesDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Elijah DixonDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Zhi TanDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Pamela MathuraDepartment of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Indraneel DattaDepartment of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Rohan N LallDepartment of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Jennifer LandryDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Evan P MintyDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Gregory A SamisDepartment of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Gerald B WinkelaarDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Neesh PannuDepartment of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acute kidney injury (AKI) is common in the perioperative setting and associated with poor outcomes. Whether clinical decision support improves early management and outcomes of AKI on surgical units is uncertain. Methods: In this cluster-randomized, stepped-wedge trial, 8 surgical units in Alberta, Canada were randomized to various start dates to receive an education and clinical decision support intervention for recognition and early management of AKI. Eligible patients were aged ≥18 years, receiving care on a surgical unit, not already receiving dialysis, and with AKI. Results: There were 2135 admissions of 2038 patients who met the inclusion criteria; mean (SD) age was 64.3 (16.2) years, and 885 (41.4%) were females. The proportion of patients who experienced the composite primary outcome of progression of AKI to a higher stage, receipt of dialysis, or death was 16.0% (178 events/1113 admissions) in the intervention group; and 17.5% (179 events/1022 admissions) in the control group (time-adjusted odds ratio, 0.76; 95% confidence interval [CI], 0.53-1.08; Conclusion: An education and clinical decision support intervention did not significantly improve processes of care or reduce progression of AKI, length of hospital stays, or recovery of kidney function in patients with AKI on surgical units.

Indexed as

acute kidney injuryclinical decision supportcluster randomized trial

Identifiers

PMID39430177
PMCPMC11489824

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.