Evidence map›Paper›PMID 39430099›Full record

ReviewDiscovery immunology2024

Unravelling monocyte functions: from the guardians of health to the regulators of disease.

Alexander Mildner, Ki-Wook Kim, Simon Yona

Abstract readReview
In one paragraph

Review in Discovery immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Monocytes/Macrophages and Atherogenesis.International journal of molecular sciences · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Multi-talented myeloid cells.Discovery immunology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexander MildnerMediCity Research Laboratory, University of Turku, Turku, Finland.
Ki-Wook KimDepartment of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, Illinois, USA.
Simon YonaInstitute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel.ORCID https://orcid.org/0000-0002-3984-2008

Funding

Role of membrane-associated macrophages in health and inflammationR01DK126753 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KIM, KIWOOK · 2021 to 2025
$2.1M
NIDDK NIH HHS R01 DK126753
6 · The paper itself

Abstract

Monocytes are a key component of the innate immune system. They undergo intricate developmental processes within the bone marrow, leading to diverse monocyte subsets in the circulation. In a state of healthy homeostasis, monocytes are continuously released into the bloodstream, destined to repopulate specific tissue-resident macrophage pools where they fulfil tissue-specific functions. However, under pathological conditions monocytes adopt various phenotypes to resolve inflammation and return to a healthy physiological state. This review explores the nuanced developmental pathways and functional roles that monocytes perform, shedding light on their significance in both physiological and pathological contexts.

Indexed as

cancerhaematopoiesis and metabolic diseaseinflammationmacrophagesmonocytes

Identifiers

PMID39430099
PMCPMC11486918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.