Evidence map›Paper›PMID 39430030›Full record

ArticleInternational journal of ophthalmology2024

αB-crystallin mini-peptides support corneal healing

Namrata Maity, Aditya Konar, Sarbani Hazra

Abstract read
In one paragraph

Article in International journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Namrata MaityDepartment of Veterinary Surgery & Radiology, West Bengal University of Animal and Fishery Sciences, Kolkata 700037, India.
Aditya KonarCSIR-IICB, Kolkata 700032, India.
Sarbani HazraDepartment of Veterinary Surgery & Radiology, West Bengal University of Animal and Fishery Sciences, Kolkata 700037, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate if topical use of αB-crystallin mini-peptides supports corneal healing following flap surgery.

methodsCultured corneal cells were treated with fluorescent tagged αB-crystallin mini-peptides to assess its internalization. Cultured corneal cells pre-treated with or without the mini-peptides were exposed to H

resultsInternalization of αB-crystallin mini-peptides was ascertained by the detection of fluorescence within the corneal cells. The MTT assay revealed that treatment with αB-crystallin mini-peptide reduced cell death induced by H

conclusionThe αB-crystallin mini-peptides restrict the damage to corneal cells and neurons and aids in corneal healing.

Indexed as

corneal healingcyto-protectionneuroprotectionαB-crystallin

Identifiers

PMID39430030
PMCPMC11422379

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.