Evidence map›Paper›PMID 39430018›Full record

ReviewInternational journal of ophthalmology2024

Application of transgenic mice to the molecular pathogenesis of cataract.

Yue Zhang, Xiao-Ya Chen, Yu-Zhu Hu, Xiao Zhang, Shun-Fei Zheng, Shan-Shan Hu

Abstract readReview
In one paragraph

Review in International journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yue ZhangMudanjiang Medical University, Mudanjiang 157011, Heilongjiang Province, China.
Xiao-Ya ChenMudanjiang Medical University, Mudanjiang 157011, Heilongjiang Province, China.
Yu-Zhu HuMudanjiang Medical University, Mudanjiang 157011, Heilongjiang Province, China.
Xiao ZhangMudanjiang Medical University, Mudanjiang 157011, Heilongjiang Province, China.
Shun-Fei ZhengMudanjiang Medical University, Mudanjiang 157011, Heilongjiang Province, China.
Shan-Shan HuDepartment of Ophthalmology, Hongqi Hospital of Mudanjiang Medical University, Mudanjiang 157011, Heilongjiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most prevalent disorders that cause blindness worldwide is cataract, and its essence is the visual disorder caused by the opacity of the lens. The significant degree of variation in cataracts and the fact that a variety of factors can impact a patient's lens transparency make it especially crucial to investigate the pathogenesis of cataracts at the molecular level. It has been found that more than 60 genes are linked to the formation of cataracts, and the construction of a transgenic mouse model of cataract similar to the selection of human lens clouding due to a variety of causes has become an important means of studying the pathogenesis of cataract. Therefore, the research on the application of transgenic mice to the molecular pathogenesis of cataracts will be the main topic of this review of the literature.

Indexed as

cataractlenstransgenic mice

Identifiers

PMID39430018
PMCPMC11422363

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.