Evidence map›Paper›PMID 39429984›Full record

ArticleCureus2024

Relationship Between the Serum Cortisol, Insulin, Adrenocorticotropic Hormone (ACTH), and Blood Glucose Levels of Pregnant Women With Gestational Diabetes Mellitus in the Kingdom of Bahrain.

Tarik AlShaibani, Wadeea Gherbal, Amer Almarabheh, Diaa Rizk, Moudhi Esmaeel, Reem Alhouli, Nora AlGhareeb, Hajar Alenezi, Sharifa Alzayani, Husain Taha and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tarik AlShaibaniPhysiology Department, College of Medicine and Health Sciences, Arabian Gulf University, Manama, BHR.
Wadeea GherbalObstetrics and Gynecology Department, Salmaniya Medical Complex, Manama, BHR.
Amer AlmarabhehFamily and Community Medicine Department, College of Medicine and Health Sciences, Arabian Gulf University, Manama, BHR.
Diaa RizkObstetrics and Gynaecology Department, College of Medicine and Health Sciences, Arabian Gulf University, Manama, BHR.
Moudhi EsmaeelPhysiology Department, College of Medicine and Health Sciences, Arabian Gulf University, Manama, BHR.
Reem AlhouliPhysiology Department, College of Medicine and Health Sciences, Arabian Gulf University, Manama, BHR.
Nora AlGhareebPhysiology Department, College of Medicine and Health Sciences, Arabian Gulf University, Manama, BHR.
Hajar AleneziPhysiology Department, College of Medicine and Health Sciences, Arabian Gulf University, Manama, BHR.
Sharifa AlzayaniPhysiology Department, College of Medicine and Health Sciences, Arabian Gulf University, Manama, BHR.
Husain TahaInternal Medicine Department, Endocrine Unit, Salmaniya Medical Complex, Manama, BHR.
Amal A HassaniObstetrics and Gynecology Department, Salmaniya Medical Complex, Manama, BHR.
Yahya NaguibPhysiology Department, College of Medicine and Health Sciences, Arabian Gulf University, Manama, BHR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Gestational diabetes mellitus (GDM) can be defined as hyperglycemia that develops during pregnancy. GDM poses both maternal and fetal potential risks. Elevated maternal cortisol levels have been linked to maternal hyperglycemia and insulin resistance. The present study aimed to investigate the relationship between GDM and serum cortisol levels in Bahraini and non-Bahraini pregnant women in the Kingdom of Bahrain. We also investigated the relationship between age and ethnicity in the development of GDM. Methods Data were collected from a total of 75 pregnant women; 41 of which were diagnosed with GDM and 34 had normal blood glucose levels. Serum cortisol, insulin, adrenocorticotropic hormone (ACTH), fasting (FBG), and random (RBG) blood glucose levels were measured. Results FBG, RBG, and insulin blood levels were significantly higher in the GDM group when compared to the control group. Serum cortisol and ACTH levels tended to be higher in the GDM group; however, they were statistically insignificant. Within the GDM group, there were no statistically significant differences in serum insulin, cortisol, and ACTH levels between Bahraini and non-Bahraini patients or between patients less than or more than 30 years old. Conclusion Our results suggest that cortisol may not have a major role in the development of GDM in our patients. Further research is needed to confirm these results. This study highlights the necessity to better understand the underlying mechanisms of the development of GDM in pregnant women.

Indexed as

cortisolgestational diabetes mellitusglucoseinsulinpregnancystressstress hormones.

Identifiers

PMID39429984
PMCPMC11488653

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.