Evidence map›Paper›PMID 39429958›Full record

ReviewInternational journal of general medicine2024

The Relationship Between Alzheimer's Disease and Pyroptosis and the Intervention Progress of Traditional Chinese Medicine.

Zixuan Zhang, Jing Bai, Siqi Zhang, Renzhen Wang, Shaobing Zhu, Tianyue Li, Miao Zhang

Abstract readReview
In one paragraph

Review in International journal of general medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zixuan ZhangGraduate Schools, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, People's Republic of China.
Jing BaiGraduate Schools, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, People's Republic of China.
Siqi ZhangGraduate Schools, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, People's Republic of China.
Renzhen WangGraduate Schools, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, People's Republic of China.
Shaobing ZhuGraduate Schools, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, People's Republic of China.
Tianyue LiGraduate Schools, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, People's Republic of China.
Miao ZhangAcupuncture and Moxibustion 10 Departments, The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disease caused by multiple causes. The main pathological features of AD are β-amyloid (Aβ) deposition, hyperphosphorylation of Tau protein, and progressive neuronal loss. Pyroptosis is one of the main forms of neuronal death, which is mainly caused by the activation of Gasdermin protein by upstream signals and the release of its N-terminal domain on the cell membrane. Studies have shown that there is a close relationship between Alzheimer's disease (AD) and pyroptosis. Therefore, this paper summarizes the relationship between pyroptosis and its molecular mechanism and AD, as well as the related research of traditional Chinese medicine in the treatment of AD by regulating pyroptosis, in order to provide a new direction for the study of AD pathogenesis based on pyroptosis pathway.

Indexed as

Alzheimer’s diseasecell pyroptosisinflammasometraditional Chinese medicine

Identifiers

PMID39429958
PMCPMC11491066

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.