Evidence map›Paper›PMID 39429923›Full record

ArticleRSC advances2024

New triazole-based hybrids as neurotropic agents.

Samvel N Sirakanyan, Domenico Spinelli, Athina Geronikaki, Elmira K Hakobyan, Anti Petrou, Victor G Kartsev, Hasmik A Yegoryan, Ervand G Paronikyan, Luca Zuppiroli, Hasmik V Jughetsyan and 3 more

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Design, Synthesis, and Pharmacological Activity of theMolecules (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Samvel N SirakanyanScientific Technological Center of Organic and Pharmaceutical Chemistry of National Academy of Science of Republic of Armenia, Institute of Fine Organic Chemistry of A.L. Mnjoyan 0014 Armenia shnnr@mail.ru.ORCID https://orcid.org/0000-0002-6056-1446
Domenico SpinelliDipartimento di Chimica G. Ciamician, Alma Mater Studiorum-Università di Bologna Via F. Selmi 2 Bologna 40126 Italy domenico.spinelli@unibo.it.
Athina GeronikakiAristotle University of Thessaloniki, School of Pharmacy Thessaloniki-54124 Greece geronik@pharm.auth.gr.
Elmira K HakobyanScientific Technological Center of Organic and Pharmaceutical Chemistry of National Academy of Science of Republic of Armenia, Institute of Fine Organic Chemistry of A.L. Mnjoyan 0014 Armenia shnnr@mail.ru.
Anti PetrouAristotle University of Thessaloniki, School of Pharmacy Thessaloniki-54124 Greece geronik@pharm.auth.gr.
Victor G KartsevInterBioScreen Moscow 119019 Russia vkartsev@ibscreen.chg.ru.
Hasmik A YegoryanScientific Technological Center of Organic and Pharmaceutical Chemistry of National Academy of Science of Republic of Armenia, Institute of Fine Organic Chemistry of A.L. Mnjoyan 0014 Armenia shnnr@mail.ru.
Ervand G ParonikyanScientific Technological Center of Organic and Pharmaceutical Chemistry of National Academy of Science of Republic of Armenia, Institute of Fine Organic Chemistry of A.L. Mnjoyan 0014 Armenia shnnr@mail.ru.
Luca ZuppiroliDepartment of Industrial Chemistry 'Toso Montanari', Alma Mater Studiorum-Università di Bologna Viale del Risorgimento 4 Bologna 40136 Italy luca.zuppiroli@unibo.it.
Hasmik V JughetsyanScientific Technological Center of Organic and Pharmaceutical Chemistry of National Academy of Science of Republic of Armenia, Institute of Fine Organic Chemistry of A.L. Mnjoyan 0014 Armenia shnnr@mail.ru.
Ruzanna G ParonikyanScientific Technological Center of Organic and Pharmaceutical Chemistry of National Academy of Science of Republic of Armenia, Institute of Fine Organic Chemistry of A.L. Mnjoyan 0014 Armenia shnnr@mail.ru.
Tatevik A ArakelyanScientific Technological Center of Organic and Pharmaceutical Chemistry of National Academy of Science of Republic of Armenia, Institute of Fine Organic Chemistry of A.L. Mnjoyan 0014 Armenia shnnr@mail.ru.
Anush A HovakimyanScientific Technological Center of Organic and Pharmaceutical Chemistry of National Academy of Science of Republic of Armenia, Institute of Fine Organic Chemistry of A.L. Mnjoyan 0014 Armenia shnnr@mail.ru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we describe the synthesis of new hybrids linked to 1,2,3- and 1,2,4-triazole units. Hybrids connected to a 1,2,3-triazole ring were synthesized using the well-known click reaction. The synthesis of the 1,2,4-triazole-based hybrids was carried out using 2-[(4-cyano-1-methyl(2-furyl)-5,6,7,8-tetrahydroisoquinolin-3-yl)oxy]acetohydrazides as starting compounds. The compounds were evaluated for their anticonvulsive activity

Identifiers

PMID39429923
PMCPMC11487511

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.