Evidence map›Paper›PMID 39429726›Full record

ArticleDiscover water2024

Potential toxic effects linked to taurine interactions with alkanolamines and diisopropylamine.

Erica Pensini, Caitlyn Hsiung, Nour Kashlan

Abstract read
In one paragraph

Article in Discover water, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Erica PensiniSchool of Engineering, College of Engineering and Physical Sciences, University of Guelph, 50 Stone Rd E, Guelph, ON N1G 2W1 Canada.ORCID 0000-0003-1494-9789
Caitlyn HsiungSchool of Engineering, College of Engineering and Physical Sciences, University of Guelph, 50 Stone Rd E, Guelph, ON N1G 2W1 Canada.
Nour KashlanSchool of Engineering, College of Engineering and Physical Sciences, University of Guelph, 50 Stone Rd E, Guelph, ON N1G 2W1 Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diisopropylamine (DIPA), aminomethyl propanol (AMP), amino ethoxy ethanol (AEE), diethanolamine (DEA), ethanolamine (EA), pyridine (PYR) and methyl diethanolamine (MDEA) are used for carbon capture and to sweeten sour gas, and are found in groundwater. They are also used in cosmetic products. Taurine is abundant in the body, with key biological functions linked to its charged SO groups. Interactions between SO and amines have not been studied, but can strongly affect the biological function of taurine. Fourier transform infrared spectroscopy indicates SO…HN hydrogen bonding between taurine and DIPA, AMP, AEE, DEA, EA and MDEA. These interactions induce the formation of hydrophobic amine-taurine clusters, thus decreasing amine miscibility in water, as revealed by light scattering. This effect is most marked for DIPA, leading to turbid mixtures indicative of micron-sized droplets. PYR and taurine likely interact via S…N bonding. This study offers insights regarding potential mechanisms of amine toxicity to humans. Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s43832-024-00146-1.

Indexed as

AminesAttenuated total reflectance—Fourier transform infrared spectroscopyGroundwater pollutionMolecular interactionsTaurine

Identifiers

PMID39429726
PMCPMC11489302

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.