Evidence map›Paper›PMID 39429479›Full record

ArticlePatient preference and adherence2024

Vitamin D Supplementation Selectively Affects Peripheral Lymphocyte Subsets in Infertile Women.

Junmei Fan, Jinghui Zhao, Junkun Zhang, Yanhua Chen, Xingyu Bi, Huiping Liu, Junfen Liu, Jinbao Wang, Xueqing Wu

Abstract read
In one paragraph

Article in Patient preference and adherence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junmei Fan *Department of Reproductive Medicine Center, Children's Hospital of Shanxi and Women Health Center of Shanxi, Taiyuan, Shanxi, 030013, People's Republic of China.
Jinghui Zhao *Department of Pediatric and Adolescent Gynecology, Shenzhen Children's Hospital, Shenzhen, Guangdong, 518000, People's Republic of China.
Junkun ZhangDepartment of Intensive Care Unit, Shanxi Bethune Hospital, The Third Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030000, People's Republic of China.
Yanhua ChenDepartment of Reproductive Medicine Center, Children's Hospital of Shanxi and Women Health Center of Shanxi, Taiyuan, Shanxi, 030013, People's Republic of China.
Xingyu BiDepartment of Reproductive Medicine Center, Children's Hospital of Shanxi and Women Health Center of Shanxi, Taiyuan, Shanxi, 030013, People's Republic of China.
Huiping LiuDepartment of Reproductive Medicine Center, Children's Hospital of Shanxi and Women Health Center of Shanxi, Taiyuan, Shanxi, 030013, People's Republic of China.
Junfen LiuDepartment of Reproductive Medicine Center, Children's Hospital of Shanxi and Women Health Center of Shanxi, Taiyuan, Shanxi, 030013, People's Republic of China.
Jinbao WangDepartment of Reproductive Medicine Center, Children's Hospital of Shanxi and Women Health Center of Shanxi, Taiyuan, Shanxi, 030013, People's Republic of China.
Xueqing WuDepartment of Reproductive Medicine Center, Children's Hospital of Shanxi and Women Health Center of Shanxi, Taiyuan, Shanxi, 030013, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to explore the effect of vitamin D supplementation on lymphocyte subsets in infertile women. Methods: The study involved a total of 247 patients who suffered recurrent embryo implantation failure (RIF) or recurrent spontaneous abortion (RSA) between January and December 2019 in the Reproductive Medicine Center of Children's Hospital of Shanxi and Women Health Center of Shanxi. The differences in the vitamin D and lymphocyte subsets of the two diseases, the correlation between the 25-hydroxy vitamin D and lymphocyte subsets, the changes in the lymphocyte subsets after vitamin D supplementation and the impact on pregnancy outcome were analysed. Results: The prevalence of vitamin D deficiency was 77.33% (191/247). After vitamin D supplementation, there were no significant differences in helper T cells (Th), cytotoxic T cells (Tc), Th/Tc and natural killer cells (NK) ( Conclusion: Vitamin D supplementation can reduce the level of NKT in infertile women, which may be of benefit to the pregnancy outcome of couples who experience RIF.

Indexed as

infertilitylymphocyte subsetsrecurrent embryo implantation failurerecurrent spontaneous abortionvitamin D

Identifiers

PMID39429479
PMCPMC11491086

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.