Evidence map›Paper›PMID 39429465›Full record

ArticleChem2024

Ribosomal peptides with polycyclic isoprenoid moieties.

Florian Hubrich, Sanath K Kandy, Clara Chepkirui, Chandrashekhar Padhi, Silja Mordhorst, Philipp Moosmann, Tao Zhu, Muriel Gugger, Jonathan R Chekan, Jörn Piel

Abstract read
In one paragraph

Article in Chem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Peptide Prenylation Follows Divergent Substrate Engagement Rules.Journal of the American Chemical Society · 2025
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Florian HubrichInstitute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Vladimir-Prelog Weg 4, 8093 Zürich, Switzerland.
Sanath K KandyDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro; Greensboro, NC 27402-6170, United States of America.
Clara ChepkiruiInstitute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Vladimir-Prelog Weg 4, 8093 Zürich, Switzerland.
Chandrashekhar PadhiInstitute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Vladimir-Prelog Weg 4, 8093 Zürich, Switzerland.
Silja MordhorstInstitute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Vladimir-Prelog Weg 4, 8093 Zürich, Switzerland.
Philipp MoosmannInstitute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Vladimir-Prelog Weg 4, 8093 Zürich, Switzerland.
Tao ZhuQingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences; Shandong Energy Institute; Qingdao New Energy Shandong Laboratory, Qingdao 266101, China.
Muriel GuggerInstitut Pasteur, Université Paris Cité, Collection of Cyanobacteria, F-75015 Paris, France.
Jonathan R ChekanDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro; Greensboro, NC 27402-6170, United States of America.
Jörn PielInstitute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Vladimir-Prelog Weg 4, 8093 Zürich, Switzerland.

Funding

Bioinformatic Guided Discovery and Characterization of New RiPP Natural ProductsR35GM147439 · NIGMS · UNIVERSITY OF NORTH CAROLINA GREENSBORO · PI Jonathan Rodi Chekan · 2022 to 2026
$1.8M
NIGMS NIH HHS R35 GM147439
6 · The paper itself

Abstract

Isoprenoid modifications of proteins and peptides serve fundamental biological functions and are of therapeutic interest. While C

Indexed as

biosynthesisnatural productspeptidesposttranslational modificationsRiPPsTerpenes

Identifiers

PMID39429465
PMCPMC11484575

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.