Evidence map›Paper›PMID 39429349›Full record

ReviewCureus2024

David Julius and Ardem Patapoutian: Pioneers in Sensory Biology and Neuroscience.

Charushila Rukadikar, Kadam Charulata, Satish P Dipankar, Milind A Nisargandha

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Charushila RukadikarPhysiology, All India Institute of Medical Sciences, Gorakhpur, Gorakhpur, IND.
Kadam CharulataPhysiology, Symbiosis Medical College for Women (SMCW), Pune, IND.
Satish P DipankarPhysiology, All India Institute of Medical Sciences, Mangalagiri, Mangalagiri, IND.
Milind A NisargandhaPhysiology, Sundarlal Patwa Government Medical College, Mandsaur, Mandsaur, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sensory biology is a critical area within neuroscience, exploring how organisms respond to environmental stimuli such as temperature, pain, and mechanical forces. David Julius and Ardem Patapoutian have made landmark contributions to this field by identifying crucial receptors. Julius's discovery of transient receptor potential (TRP) channels, including transient receptor potential cation channel subfamily V member 1 (TRPV1), which detects heat and pain, revolutionized sensory biology and opened new paths for pain management. Similarly, Patapoutian's identification of Piezo channels, which respond to mechanical stimuli like touch and pressure, has deepened our understanding of sensory perception. Their combined work has not only advanced scientific knowledge but also introduced potential treatments for chronic pain and sensory disorders. This paper reviews their contributions and the broader implications for sensory biology and therapeutic developments.

Indexed as

neurosciencenociceptionpain managementsensory biologytrpv1 receptor

Identifiers

PMID39429349
PMCPMC11491139

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.