Evidence map›Paper›PMID 39429221›Full record

ArticleClinical cardiology2024

Association Between Family Income, Subclinical Myocardial Injury, and Cardiovascular Mortality in the General Population.

Sneha Chebrolu, Richard Kazibwe, Elsayed Z Soliman

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Article in Clinical cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sneha ChebroluDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID http://orcid.org/0009-0001-3135-793X
Richard KazibweDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID http://orcid.org/0000-0001-7085-3373
Elsayed Z SolimanSection on Cardiovascular Medicine, Department of Medicine, Epidemiological Cardiology Research Center (EPICARE), Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

introductionBoth low family income and subclinical myocardial injury (SCMI) are risk factors for cardiovascular disease (CVD) mortality. However, the impact of their joint association on CVD mortality is unclear.

methodsThis analysis from the third National Health and Nutrition Examination Survey included 6805 participants (age 59.1 ± 13.4 years, 52.3% women, and 49.8% White) free of CVD at baseline. Family income was assessed using the poverty-income ratio (PIR) and categorized into low (PIR < 1), middle (PIR = 1-4), and high (PIR > 4) income. A validated ECG-based cardiac infarction injury score (CIIS) ≥ 10 was considered positive for SCMI. CVD mortality was determined using the National Death Index. Cox-proportional hazard analysis was used to evaluate the associations of family income and SCMI, separately and jointly, with CVD mortality.

resultsA total of 1782 (26.2%) participants had SCMI at baseline. During a median follow-up of 18.2 years, 856 (12.6%) events of CVD mortality occurred. In separate multivariable Cox models, SCMI (vs. no SCMI) and middle- and low-income (vs. high-income) were each associated with a higher risk of CVD mortality (HR [95% CI]: 1.34 [1.16-1.54], 1.44 [1.16-1.78], and 1.59 [1.22-2.07], respectively). Compared to high-income participants without SCMI, those with low-income and SCMI had an increased risk of CVD mortality (HR [95% CI]: 2.17 [1.53-3.08]). The multiplicative interaction between PIR and SCMI was not significant (p = 0.054).

conclusionLower family income and SCMI are associated with CVD mortality, and their concomitant presence is associated with the highest risk. Family income and SCMI may help in the individualized assessment of CVD risk.

Indexed as

IncomeNutrition SurveysAgedAsymptomatic DiseasesCardiovascular DiseasesElectrocardiographyFemaleHumansMaleMiddle AgedPovertyPrognosisProportional Hazards ModelsRisk AssessmentRisk FactorsTime Factorscardiovascular mortalitypoverty income ratiosocial determinants of healthsubclinical myocardial injury

Identifiers

PMID39429221
PMCPMC11491868

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.