Evidence map›Paper›PMID 39429194›Full record

ArticleVirulence2024

Synergy of bacteriophage depolymerase with host immunity rescues sepsis mice infected with hypervirulent

Deyi Zhao, Miran Tang, Zhexiao Ma, Panjie Hu, Qingxia Fu, Zhuocheng Yao, Cui Zhou, Tieli Zhou, Jianming Cao

Abstract read
In one paragraph

Article in Virulence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A systematic review of hypervirulentFrontiers in medicine · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. H-NS Regulates the Virulence ofMicroorganisms · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Deyi ZhaoSchool of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, China.
Miran TangDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Zhexiao MaSchool of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, China.
Panjie HuSchool of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, China.
Qingxia FuDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Zhuocheng YaoDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Cui ZhouDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Tieli ZhouDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.ORCID 0000-0002-2171-4710
Jianming CaoSchool of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, China.ORCID 0000-0002-9968-6721

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hypervirulent

Indexed as

Bacterial CapsulesBacteriophagesKlebsiella InfectionsKlebsiella pneumoniaeSepsisAnimalsAnti-Bacterial AgentsDisease Models, AnimalFemaleGlycoside HydrolasesMiceVirulenceAnti-Bacterial Agentscapsular-polysaccharide galactohydrolaseGlycoside Hydrolasesanti-virulence agentcapsular polysaccharidehost immunityHypervirulent K. pneumoniaephage depolymerasesepsis

Identifiers

PMID39429194
PMCPMC11497950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.