Evidence map›Paper›PMID 39429165›Full record

ArticleAllergy2024

Early-life exposure to residential greenness and risk of asthma in a U.S. bronchiolitis cohort.

Wojciech Feleszko, Heidi Makrinioti, Marta Nalej, Tadao Ooka, Zhaozhong Zhu, Ashley F Sullivan, Tuomas Jartti, Kohei Hasegawa, Carlos A Camargo

Abstract read
In one paragraph

Article in Allergy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wojciech FeleszkoDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0001-6613-2012
Heidi MakriniotiDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Marta NalejInstitute of Urban Geography, Tourism Studies and Geoinformation, Faculty of Geographical Sciences, University of Łódź, Łódź, Poland.
Tadao OokaDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Zhaozhong ZhuDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Ashley F SullivanDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Tuomas JarttiDepartment of Paediatrics, Turku University Hospital and Turku University, Turku, Finland.ORCID 0000-0003-2748-5362
Kohei HasegawaDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Funding

Host genetics, early-life microbiome, and childhood asthma: MARC-43 BostonUH3OD023253 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARLOS ARTURO CAMARGO · 2018 to 2026
$12.1M
Host genetics, early-life microbiome, and childhood asthma: MARC-43 BostonUG3OD023253 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2016 to 2024
$6.8M
Infant blood epigenome and risks of IgE sensitization, obesity, and asthma: MARC-35/43 cohortsR01AI148338 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI CAMARGO, CARLOS ARTURO, LIANG, LIMING · 2020 to 2023
$2.5M
Integrating the genome, metabolome, and microbiome for childhood asthma: Risk and endotypesK01AI153558 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI ZHU, ZHAOZHONG · 2021 to 2025
$663k
Fundacja RespiraLastentautien TutkimussäätiöNIAID NIH HHS K01 AI153558NIAID NIH HHS R01 AI148338NIH HHS UG3 OD023253NIH HHS UH3 OD023253
6 · The paper itself

Abstract

introductionSevere bronchiolitis (i.e., bronchiolitis requiring hospitalization) is linked to childhood asthma development. Despite a growing understanding of risk factors for developing post-bronchiolitis asthma, protective factors remain unclear. In this study, we aimed to investigate whether exposure to residential greenness between birth and bronchiolitis hospitalization is associated with asthma and atopic asthma development by age 6 years.

methodsWe analyzed a US severe bronchiolitis cohort from hospitalization to age 6 years, investigating how the normalized difference vegetation index (NDVI) and chlorophyll index green (CI green), measured in small (100 m) and large (500 m) radiuses around homes, relate to asthma and atopic asthma by age 6 years. We also explored whether maternal antibiotic use, daycare attendance, and respiratory virus type during hospitalization act as effect modifiers.

resultsThe study cohort included 861 infants, with 239 (28%) developing asthma by age 6 years-152 atopic, 17 nonatopic, and 70 unclassified. Early life residential exposure to high NDVI and CI green levels was associated with lower odds of asthma (OR

conclusionIn a U.S. bronchiolitis cohort, exposure to residential greenness between birth and bronchiolitis hospitalization is linked to lower asthma and atopic asthma risk by age 6 years.

Indexed as

AsthmaBronchiolitisEnvironmental ExposureChildChild, PreschoolCohort StudiesFemaleHospitalizationHumansInfantInfant, NewbornMaleOdds RatioResidence CharacteristicsRisk FactorsUnited Statesasthmabronchiolitischlorophyll indexgreennessvegetation

Identifiers

PMID39429165
PMCPMC11560528

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.