Evidence map›Paper›PMID 39429153›Full record

ArticleStroke2024

Twenty Years of Sustained Improvement in Quality of Care and Outcomes for Patients Hospitalized With Stroke or Transient Ischemic Attack: Data From The Get With The Guidelines-Stroke Program.

Ying Xian, Shen Li, Tian Jiang, Chandler D Beon, Remy Poudel, Kathie Thomas, Mathew J Reeves, Eric E Smith, Jeffrey L Saver, Kevin N Sheth and 3 more

Abstract read
In one paragraph

Article in Stroke, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Observational
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ying XianDepartment of Neurology, UT Southwestern Medical Center, Dallas, TX (Y.X.).ORCID 0000-0002-1237-1162
Shen LiAmerican Heart Association/American Stroke Association, Dallas (S.L., T.J., C.D.B., R.P., K.T.).ORCID 0000-0001-9322-6516
Tian JiangAmerican Heart Association/American Stroke Association, Dallas (S.L., T.J., C.D.B., R.P., K.T.).
Chandler D BeonAmerican Heart Association/American Stroke Association, Dallas (S.L., T.J., C.D.B., R.P., K.T.).ORCID 0000-0001-6868-0370
Remy PoudelAmerican Heart Association/American Stroke Association, Dallas (S.L., T.J., C.D.B., R.P., K.T.).ORCID 0009-0008-2028-8773
Kathie ThomasAmerican Heart Association/American Stroke Association, Dallas (S.L., T.J., C.D.B., R.P., K.T.).ORCID 0009-0006-1692-3282
Mathew J ReevesDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing (M.J.R.).ORCID 0000-0002-8019-6343
Eric E SmithDepartment of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Alberta, Canada (E.E.S.).ORCID 0000-0003-3956-1668
Jeffrey L SaverDepartment of Neurology (J.L.S.), University of California Los Angeles Medical Center.ORCID 0000-0001-9141-2251
Kevin N ShethCenter for Brain and Mind Health, Departments of Neurology and Neurosurgery (K.N.S.), Yale School of Medicine, New Haven, CT.ORCID 0000-0003-2003-5473
Steven R MesséDepartment of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.R.M.).ORCID 0000-0003-3108-5441
Lee H SchwammDepartment of Neurology and Bioinformatics and Data Sciences (L.H.S.), Yale School of Medicine, New Haven, CT.ORCID 0000-0003-0592-9145
Gregg C FonarowDivision of Cardiology (G.C.F.), University of California Los Angeles Medical Center.ORCID 0000-0002-3192-8093

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
ACTION - A CHF Trial Investigating Outcomes of ExerciseU01HL068980 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FONAROW, GREGG C · 2002 to 2006
$709k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS U01 HL068980
6 · The paper itself

Abstract

backgroundThe Get With The Guidelines-Stroke program is a quality improvement initiative designed to enhance adherence to evidence-based stroke care. Since its inception in 2003, over 2800 hospitals in the United States have participated in the program.

methodsWe examined patient characteristics, adherence to performance measures, and in-hospital outcomes in patients hospitalized for acute ischemic stroke, subarachnoid hemorrhage, intracerebral hemorrhage, and transient ischemic attack in The Get With The Guidelines-Stroke hospitals from 2003 through 2022. We quantified temporal changes in performance measure adherence and clinical outcomes over time. Performance measure denominators consisted of patients who were eligible, excluding those with contraindications.

resultsOver the 20 years of the program, a total of 7837 849 stroke cases (median age 71 years, 51.0% female; 69.2% ischemic strokes, 3.9% SAHs, 11.5% ICHs, and 15.3% TIAs) were entered into the registry. Except for antithrombotics at discharge, in which the baseline performance was >92%, there was sustained improvement in all performance metrics regardless of type of cerebrovascular event (

conclusionsDuring the first 20 years, Get With The Guidelines-Stroke participation was associated with sustained improvement in evidence-based care and outcomes for patients with stroke and transient ischemic attack in the United States.

Indexed as

Ischemic Attack, TransientQuality ImprovementAgedAged, 80 and overFemaleGuideline AdherenceHospitalizationHumansIschemic StrokeMaleMiddle AgedQuality of Health CareRegistriesStrokeTreatment OutcomeUnited Statesacute ischemic strokeintracerebral hemorrhageoutcomesquality of caretransient ischemic attack

Identifiers

PMID39429153
PMCPMC11518659

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.