Evidence map›Paper›PMID 39429119›Full record

ArticleThe British journal of nutrition2024

Choline and betaine intakes during pregnancy in relation to risk of gestational diabetes mellitus among Chinese women.

Kallie Lamkin, Lan Xu, Kaipeng Wang, Yuhong Liu, Kefeng Yang, Hui Wu, Lingpeng Lu, Xiaoxi Shen, Cassandra M Johnson, Jie Jia and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in The British journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kallie Lamkin *Nutrition and Foods Program, School of Family and Consumer Sciences, Texas State University, San Marcos, TX78666, USA.
Lan Xu *Department of Epidemiology, School of Medicine, Shanghai Jiao Tong University, Shanghai200025, People's Republic of China.
Kaipeng WangGraduate School of Social Work, University of Denver, Denver, CO80208, USA.
Yuhong LiuDepartment of Gynecology and Obstetrics, Shanghai Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai200137, People's Republic of China.
Kefeng YangDepartment of Clinical Nutrition, College of Heath Science and Technology, School of Medicine, Shanghai Jiao Tong University, Shanghai200025, People's Republic of China.
Hui WuDepartment of Clinical Nutrition, Shanghai Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai200137, People's Republic of China.ORCID 0000-0001-7830-2517
Lingpeng LuDepartment of Clinical Laboratory, Shanghai Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai200137, People's Republic of China.
Xiaoxi ShenDepartment of Mathematics, Texas State University, San Marcos, TX78666, USA.
Cassandra M JohnsonNutrition and Foods Program, School of Family and Consumer Sciences, Texas State University, San Marcos, TX78666, USA.
Jie JiaDepartment of Clinical Nutrition, College of Heath Science and Technology, School of Medicine, Shanghai Jiao Tong University, Shanghai200025, People's Republic of China.
Jie ZhuNutrition and Foods Program, School of Family and Consumer Sciences, Texas State University, San Marcos, TX78666, USA.ORCID 0000-0001-5304-7708

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous animal studies found beneficial effects of choline and betaine on maternal glucose metabolism during pregnancy, but few human studies explored the association between choline or betaine intake and incident gestational diabetes mellitus (GDM). We aimed to explore the correlation of dietary choline or betaine intake with GDM risk among Chinese pregnant women. A total of 168 pregnant women with GDM cases and 375 healthy controls were enrolled at the Seventh People's Hospital in Shanghai during their GDM screening at 24-28 gestational weeks. A validated semi-quantitative FFQ was used to estimate choline and betaine consumption through face-to-face interviews. An unconditional logistic regression model was adopted to examine OR and 95 % CI. Compared with the controls, those women with GDM incidence were likely to have higher pre-pregnancy BMI, be older, have more parities and have higher plasma TAG and lower plasma HDL-cholesterol. No significant correlation was observed between the consumption of choline or betaine and incident GDM (adjusted OR (95 % CI), 0·77 (0·41, 1·43) for choline; 0·80 (0·42, 1·52) for betaine). However, there was a significant interaction between betaine intake and parity on the risk of GDM (

Indexed as

BetaineCholineDiabetes, GestationalDietAdultBody Mass IndexCase-Control StudiesChinaEast Asian PeopleFemaleHumansIncidenceLogistic ModelsMaternal Nutritional Physiological PhenomenaParityPregnancyBetaineCholineBetaineCholineDiet intakeGestational diabetes mellitus

Identifiers

PMID39429119
PMCPMC11576091

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.