Evidence map›Paper›PMID 39429115›Full record

ArticleThe Journal of laryngology and otology2024

Outcomes of the modern management approach for locally advanced (T

Amarkumar Dhirajlal Rajgor, Josh Cowley, Colin Gillespie, Chang Woo Lee, James O'Hara, Muhammad Shahid Iqbal, David Winston Hamilton

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In one paragraph

Article in The Journal of laryngology and otology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amarkumar Dhirajlal RajgorNational Institute for Health & Care Research Doctoral Fellow in Otolaryngology, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0002-9323-3107
Josh CowleySchool of Mathematics, Newcastle University, Newcastle upon Tyne, UK.
Colin GillespieSchool of Mathematics, Newcastle University, Newcastle upon Tyne, UK.
Chang Woo LeeDepartment of Otolaryngology - Head and Neck Surgery, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0001-6552-337X
James O'HaraDepartment of Otolaryngology - Head and Neck Surgery, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Muhammad Shahid IqbalDepartment of Clinical Oncology, Northern Centre for Cancer Care, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0002-6161-9128
David Winston HamiltonDepartment of Otolaryngology - Head and Neck Surgery, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur centre (Freeman Hospital, Newcatle Upon Tyne NHS Trust) has favoured primary surgery over chemoradiotherapy for specific advanced laryngeal cancer patients (e.g. large-volume tumours, airway compromise, significant dysphagia, T

methodRetrospective analysis of patient data over a seven-year period from a tertiary cancer centre.

resultsIn total, 121 patients were identified with T

conclusionFor a centre favouring primary surgery for certain advanced laryngeal cancers, the disease-specific survival appears no higher than that found in the published literature. To enhance survival, future research should focus on precision medicine to define treatment pathways in this disease.

Indexed as

Laryngeal NeoplasmsAdultAgedAged, 80 and overChemoradiotherapyCombined Modality TherapyFemaleHumansLaryngectomyMaleMiddle AgedNeoplasm StagingRetrospective StudiesSurvival RateTreatment Outcomechemoradiotherapyhead and neck surgerylarynxoncology

Identifiers

PMID39429115
PMCPMC11735189

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.