ArticleInternal medicine (Tokyo, Japan)2025
Possible Case of Elderly-onset Intestinal Behçet's Disease with Trisomy 8 Following COVID-19 Vaccination Exacerbated by COVID-19 Infection.
Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- The Possible Genetic and Environmental Factors Related to Behçet's Disease: Trisomy 8 and SARS-CoV-2.Internal medicine (Tokyo, Japan) · 2025Article
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9 authors.
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Abstract
Coronavirus disease 2019 (COVID-19) vaccines are effective in reducing the prevalence of this disease. However, some patients develop autoimmune diseases after vaccination. We herein report a case of elderly onset intestinal Behçet's disease (BD) with trisomy 8 following COVID-19 vaccination in which the disease was exacerbated by COVID-19 infection. The patient developed refractory stomatitis and genital ulcers two weeks after receiving the second vaccination and presented with bloody stool two years later. Intestinal BD with trisomy 8, exacerbated by COVID-19, was treated with high-dose glucocorticoids and infliximab; however, surgical intervention was required. The findings of this case suggest that the COVID-19 vaccination may induce BD.
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