Evidence map›Paper›PMID 39428442›Full record

ArticleInternational urology and nephrology2025

Prediction of complications after laparoscopic partial nephrectomy: feasibility of E‑PASS score.

Sinan Celen, Alper Simsek, Mesut Berkan Duran, Kursat Kucuker, Burak Saglam, Oguz Celik, Yusuf Ozlulerden

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Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Sinan CelenDepartment of Urology, Pamukkale University Hospital, Denizli, Turkey.ORCID http://orcid.org/0000-0003-4309-2323
Alper SimsekDepartment of Urology, Siverek State Hospital, Ediz Şanlıurfa Diyarbakır Yolu 8. Km Siverek, 63600, Sanliurfa, Turkey. drsimsekalper@gmail.com.ORCID http://orcid.org/0000-0002-0513-4505
Mesut Berkan DuranDepartment of Urology, Pamukkale University Hospital, Denizli, Turkey.ORCID http://orcid.org/0000-0002-8597-2081
Kursat KucukerDepartment of Urology, Pamukkale University Hospital, Denizli, Turkey.ORCID http://orcid.org/0000-0002-5558-327X
Burak SaglamDepartment of Urology, Pamukkale University Hospital, Denizli, Turkey.ORCID http://orcid.org/0009-0007-1363-8360
Oguz CelikDepartment of Urology, Pamukkale University Hospital, Denizli, Turkey.ORCID http://orcid.org/0000-0002-1052-4225
Yusuf OzlulerdenDepartment of Urology, Pamukkale University Hospital, Denizli, Turkey.ORCID http://orcid.org/0000-0002-6467-0930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWith significant advancements in laparoscopic procedures and tools over the last decade, the partial nephrectomy (PN) surgical approach has gradually transformed from open to laparoscopic partial nephrectomy (LPN). Although numerous studies evaluating the postoperative complications of laparoscopic partial nephrectomy can be found in the literature, a scoring system that addresses both preoperative physical condition and intraoperative risk factors has not yet been established. The Estimation of Physiological Ability and Surgical Stress (E-PASS) score is a scoring system that considers both the patient's preoperative condition and intraoperative variables to predict the risk of postoperative complications in surgically treated patients. This study aimed to assess the applicability of the E-PASS scoring system for predicting postoperative complications following LPN.

methodsWe analyzed data of 196 patients who underwent LPN between 2017 and 2024 by a single surgeon in this single-center retrospective study. Demographic data of the patients, parameters reflecting patients' preoperative physical condition, and intraoperative risk factors were recorded. Postoperative complications were classified using the Clavien-Dindo system. The E-PASS score and its sub-scores were calculated for each patient.

resultsVarious degrees of complications developed in 46 patients (23.5%). Patients who developed complications had significantly higher mean age, performance scores, tumor sizes, length of hospital stay, and E-PASS values. The cutoff value of the E-PASS Comprehensive Risk Score (CRS) for predicting the development of postoperative complications was determined to be - 0.1692 (AUC = 0.676; 95% CI 0.581-0.771; p < 0.001). According to the results of the multivariate analysis, the presence of E-PASS CRS > - 0.1692 (OR 4.872; 95% CI 2.384-9.957; p < 0.001) and tumor size (OR 1.021; 95% CI 1-1.041; p = 0.047) was identified as independent risk factors predicting postoperative complications. Patients with a CRS higher than the cutoff value had a 4.87 times higher rate of postoperative complications after LPN.

conclusionThe E-PASS scoring model successfully predicts postoperative complications in patients undergoing LPN by utilizing preoperative data on the patient's physical condition and surgical risk factors. The E-PASS score and its sub-scores can serve as objective criteria to determine the risk of postoperative complications both preoperatively and immediately postoperatively.

Indexed as

Kidney NeoplasmsLaparoscopyNephrectomyPostoperative ComplicationsAdultAgedFeasibility StudiesFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsE-PASS scoreLaparoscopic partial nephrectomyPostoperative complications

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.