Evidence map›Paper›PMID 39427534›Full record

ArticleDrug and alcohol dependence2024

Psychometric performance of tools to measure internalized drug use stigma among people who use drugs and people on medication-assisted treatment in Dar es Salaam, Tanzania.

Stacy M Endres-Dighe, Linda B Mlunde, Emmanuel Oga, Jessie K Mbwambo, Zawadi Shomari, Judith Mkufya, Elizabeth Nguma, Lucy C Teemba, Khalida Saalim, Laura Nyblade

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Stacy M Endres-DigheThe Ohio State University, College of Public Health, Department of Epidemiology, 1841 Neil Avenue, Columbus, OH 43210, United States; RTI International, Social, Statistical and Environmental Sciences, 3040 East Cornwallis Drive, Durham, NC 27709, United States. Electronic address: endres-dighe.1@buckeyemail.osu.edu.
Linda B MlundeMuhimbili University of Health and Allied Sciences, School of Public Health and Social Sciences, Department of Community Health, P.O. Box 65001, Dar es Salaam, Tanzania.
Emmanuel OgaRTI International, Social, Statistical and Environmental Sciences, 3040 East Cornwallis Drive, Durham, NC 27709, United States.
Jessie K MbwamboMuhimbili University of Health and Allied Sciences, Department of Psychiatry and Mental Health, P.O. Box 65001, Dar es Salaam, Tanzania; Muhimbili National Hospital, Department of Psychiatry and Mental Health, P.O. Box 65000, Dar es Salaam, Tanzania.
Zawadi ShomariMuhimbili University of Health and Allied Sciences, School of Public Health and Social Sciences, Department of Community Health, P.O. Box 65001, Dar es Salaam, Tanzania.
Judith MkufyaMuhimbili University of Health and Allied Sciences, School of Public Health and Social Sciences, Department of Community Health, P.O. Box 65001, Dar es Salaam, Tanzania.
Elizabeth NgumaMuhimbili University of Health and Allied Sciences, School of Public Health and Social Sciences, Department of Community Health, P.O. Box 65001, Dar es Salaam, Tanzania.
Lucy C TeembaMuhimbili University of Health and Allied Sciences, School of Public Health and Social Sciences, Department of Community Health, P.O. Box 65001, Dar es Salaam, Tanzania.
Khalida SaalimMuhimbili National Hospital, Department of Psychiatry and Mental Health, P.O. Box 65000, Dar es Salaam, Tanzania.
Laura NybladeRTI International, Social, Statistical and Environmental Sciences, 3040 East Cornwallis Drive, Durham, NC 27709, United States.

Funding

RTI HEAL Harm Reduction Network Coordination CenterR24DA057611 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI CANCE, JESSICA DUNCAN, OGA, EMMANUEL AJA · 2022 to 2023
$1.6M
Improving HIV treatment outcomes for people who use drugs: adapting and piloting a drug-use use stigma-reduction intervention in HIV care and treatment clinics in TanzaniaR21TW011786 · FIC · RESEARCH TRIANGLE INSTITUTE · PI NYBLADE, LAURA · 2020 to 2021
$535k
Examining the mediating effect of resilience on intersectional stigma and HIV prevention among people who inject drugs in rural Appalachia OhioR36DA060059 · NIDA · OHIO STATE UNIVERSITY · PI ENDRES-DIGHE, STACY M. · 2023 to 2023
$53k
FIC NIH HHS R21 TW011786NIDA NIH HHS R24 DA057611NIDA NIH HHS R36 DA060059
6 · The paper itself

Abstract

backgroundPeople who use drugs (PWUD) and people who use medication-assisted treatment (MAT) to treat opioid use disorder face severe stigma. Stigma may manifest in delayed health-seeking behaviors, which adversely affects health and increases disease risk. Few validated measures assess internalized drug use stigma or MAT disclosure concerns in sub-Saharan Africa. This study examines the performance of internalized drug use stigma scales and characterizes the prevalence of these stigmas among PWUD and people who use MAT in Dar es Salaam, Tanzania.

methodsWe conducted a cross-sectional survey among 250 PWUD and 251 MAT clinic clients. Internalized drug use and MAT disclosure concerns were measured using scales adapted to the Tanzanian context. We conducted exploratory factor analysis to identify latent constructs and evaluate reliability of the scales. We then used confirmatory factor analysis to assess construct validity and reliability.

resultsThe six-item internalized drug use stigma scale (IDUSS) was unidimensional, reflected acceptable goodness-of-fit, and acceptable reliability (Cronbach's α = 0.79). The eight-item internalized drug use stigma scale for people using MAT (IDUSS-MAT) was bidimensional. Allowing error terms of related items to covary improved goodness-of-fit. The IDUSS-MAT demonstrated acceptable reliability (Cronbach's α = 0.79). Among PWUD and MAT clinic clients, higher levels of stigma were associated with increased depression and reduced social support and quality of life.

conclusionsBoth the IDUSS and IDUSS-MAT demonstrated good construct validity and acceptable reliability. These validated scales provide the foundation for collecting data to inform the development of stigma reduction interventions in Tanzania and among similar Sub-Saharan populations of PWUD and the tools needed to assess those interventions.

Indexed as

PsychometricsSocial StigmaAdultCross-Sectional StudiesDrug UsersFemaleHumansMaleMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersReproducibility of ResultsSubstance-Related DisordersSurveys and QuestionnairesTanzaniaYoung AdultIllicit drug useMedication-assisted treatmentStigmaSubstance use disorderTanzania

Identifiers

PMID39427534
PMCPMC11830454

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.