Evidence map›Paper›PMID 39427436›Full record

ReviewUltrasonics sonochemistry2024

Progress in application of nanomedicines for enhancing cancer sono-immunotherapy.

Hongxin Zhao, Fangxue Du, Xi Xiang, Yuanjiao Tang, Ziyan Feng, Ziyao Wang, Xiao Rong, Li Qiu

Abstract readReview
In one paragraph

Review in Ultrasonics sonochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hongxin ZhaoDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China.
Fangxue DuDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China.
Xi XiangDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China.
Yuanjiao TangDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China.
Ziyan FengDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China.
Ziyao WangDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China.
Xiao RongDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address: rongxiaous@163.com.
Li QiuDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address: qiulihx@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer immunotherapy has significant potential as a cancer treatment since it boosts the immune system and prevents immune escape to get rid of or fight cancers. However, its clinical applicability is still limited because of the low response rate and immune-related side effects. Recently ultrasound has been shown to alter the tumor immune microenvironment, enhance the effectiveness of other antitumor therapies, and cause tumors to become more sensitive to immunotherapy, thus providing new insights into cancer treatment. Nanomedicines are also anticipated to have a positive impact on improving the immunological effects and enhancing ultrasound effect for cancer therapy. Therefore, designing effective nanomedicines enhanced ultrasound effect for augmenting sono-immunotherapy has been a pivot on anticancer therapy. In this review, the immunological impacts of various ultrasound therapeutic modalities, ultrasound parameters, and their underlying mechanisms are discussed. Moreover, we highlight the recent progress of nanomedicines synergistically enhancing sono-immunotherapy. Finally, we put forward opportunities and challenges on sono-immunotherapy.

Indexed as

ImmunotherapyNanomedicineNeoplasmsAnimalsHumansTumor MicroenvironmentUltrasonic TherapyNanomedicinesSonodynamic therapySono-immunotherapyUltrasound-mediated micro-/nanobubble destruction

Identifiers

PMID39427436
PMCPMC11533716

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.