ArticleCell reports2024
Dissociable contributions of the amygdala and ventral hippocampus to stress-induced changes in defensive behavior.
Article in Cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Article
- Prior trauma shapes the effects of psilocybin on stress sensitization in mice.Neuroscience letters · 2026Article
- Resetting the hippocampal buffer: a neurocognitive account of psychedelic therapy for anxiety-related psychopathology.Psychopharmacology · 2026Review
- The ventral hippocampus: computations, circuits and functions.Nature reviews. Neuroscience · 2026Review
- Neural mechanisms of fear memory precision and generalization: from auditory cortex to amygdala.Translational psychiatry · 2026Review
- Article
- Grooming as a window into the post-stress recuperative process.bioRxiv : the preprint server for biology · 2026Article
- Targeting the 5-HTCell & bioscience · 2026Article
- Stress-Enhanced Fear Learning (SEFL) Is Associated With Enhanced Reactivation of Fear Engrams in Caudal But Not Rostral Dentate Gyrus.Hippocampus · 2026Article
- Stress-Enhanced Fear Learning (SEFL) is Associated with Enhanced Reactivation of Fear Engrams in Caudal but not Rostral Dentate Gyrus.bioRxiv : the preprint server for biology · 2026Article
- Sexually dimorphic effects of single prolonged stress on conditioned suppression behavior in Long Evans rats with no detection of altered mRNA expression of VGLUT1, GAD1, and Arc in the ventral hippocampus.Frontiers in behavioral neuroscience · 2026Article
- Crocin alleviates neuronal arborization damage in the basolateral nucleus of the amygdala and dentate gyrus of the hippocampus in a stressed rat.IBRO neuroscience reports · 2025Article
- Capgras Syndrome Triggered by Marital Separation: A Rare Case of Trauma-Induced Delusional Misidentification.Cureus · 2025Article
- Stress induces distinct social behavior states encoded by the ventral hippocampus.bioRxiv : the preprint server for biology · 2025Article
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15 authors.
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Abstract
Stress can have profound consequences on mental health. While much is known about the neural circuits supporting associative memories of stressful events, our understanding of the circuits underlying the non-associative impacts of stress, such as heightened stress sensitivity and anxiety-related behavior, is limited. Here, we demonstrate that the ventral hippocampus (vHC) and basolateral amygdala (BLA) support distinct non-associative behavioral changes following stress. Inhibiting stress-induced protein synthesis in the BLA blocked subsequent increases in stress sensitivity but not anxiety-related behaviors. Conversely, inhibiting stress-induced protein synthesis in the vHC blocked subsequent increases in anxiety-related behavior but not stress sensitivity. Inhibiting neuronal activity in the BLA and vHC during the assessment of stress sensitivity or anxiety-related behavior recapitulated these structures' dissociable contributions to defensive behavior. Lastly, blocking the associative memory of a stressor had no impact on stress-induced changes in anxiety-related behavior. These findings highlight that multiple memory systems support the long-lasting effects of stress.
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