ArticleAnnals of intensive care2024
Predicting outcomes in patients with exacerbation of COPD requiring mechanical ventilation.
Article in Annals of intensive care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Predictive models for mortality readmission events and cardiovascular complications in patients with COPD: a systematic review and meta-analysis.ERJ open research · 2026Article
- Acute hYpErcapnic respiratory failure in The ICU: A multicenter prospective observational study - The YETI study.Annals of intensive care · 2026Article
- Relationship Between Systemic Immune-Inflammation Index and In-Hospital Mortality in Sepsis Combined With Chronic Obstructive Pulmonary Disease Modified by Mechanical Ventilation.The clinical respiratory journal · 2025Article
- Impact of Increased Use of Single-Inhaler Triple Therapies on COPD Exacerbation Rates, Mortality, and Total Costs: PROMETHEUS France.International journal of chronic obstructive pulmonary disease · 2025Article
- Predictors of Clinical Stability and Mortality in COPD: A Longitudinal Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Factors Influencing Mechanical Ventilation and Inpatient Palliative Care Utilization in Patients With Chronic Obstructive Pulmonary Disease.Journal of multidisciplinary healthcare · 2025Article
- Association between serum calcium levels and the risk of invasive mechanical ventilation in COPD: a retrospective cohort study.Frontiers in medicine · 2025Article
- Predicting in-hospital mortality in a real-world population of ward-based non-invasive ventilation in acute COPD exacerbations.Therapeutic advances in respiratory diseaseObservational
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Authors and funding
5 authors.
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Abstract
backgroundAcute exacerbations of COPD (AECOPD) are common and significantly contribute to mortality in patients with COPD. Prognostic scores can assist clinicians in making tailored decisions to manage AECOPD. In the current study, we therefore aimed to evaluate the performance of the Noninvasive Ventilation Outcomes (NIVO) score, originally designed to assess in-ICU mortality, in predicting 1 year mortality and NIV failure in AECOPD.
methodsThis retrospective study analyzed data from patients hospitalized for AECOPD requiring mechanical ventilation between January 1st, 2018, and December 31st, 2022. Mortality was assessed at the end of ICU stay and 1 year after admission, while NIV failure was defined as intubation or death without intubation.
resultsAmong 302 ICU admissions of COPD patients, 190 patients with AECOPD requiring mechanical ventilation were included. Of these, 44 (23%) died in the ICU, 62 out of 184 (34%) failed NIV, and 78 (41%) died within 1 year of admission. Patients who died in ICU or experienced NIV failure had more severe COPD and more impaired blood gas parameters at admission. The NIVO score demonstrated an AUC of 0.68 in predicting 1-year mortality and an AUC of 0.85 in predicting NIV failure. A NIVO score over 7 was associated with higher 1-year mortality and NIV failure (HR of 4.4 [1.8-10.9] and 41.6 [5.6-307.9], respectively).
conclusionBeyond predicting in-ICU mortality, the NIVO-score is a reliable tool in predicting 1-year mortality and NIV failure in AECOPD.
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