Evidence map›Paper›PMID 39427230›Full record

Trial reportAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2025

Cognitive Health Benefits of Everyday Physical Activity in a Diverse Sample of Middle-Aged Adults.

Jonathan G Hakun, Lizbeth Benson, Tian Qiu, Daniel B Elbich, Mindy Katz, Pamela A Shaw, Martin J Sliwinski, Yasmin Mossavar-Rahmani

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03240406 (Multicultural Healthy Diet to Reduce Cognitive Decline & Alzheimer's Disease Risk), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03240406 nacompletednot on this map

Multicultural Healthy Diet to Reduce Cognitive Decline & Alzheimer's Disease Risk

TypeinterventionalSponsorAlbert Einstein College of MedicineRan2018 to 2023Enrolled393ConditionsDiet Modification, Cognitive Decline, Cognitive ChangeArmsMulticultural Healthy Diet, Usual Diet plus Self-Care
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Not just how much, but how it's done: movement activity bout distributions and everyday cognition in older adults with elevated dementia risk.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Combinations of light, moderate, and vigorous physical activity in midlife and old age: implications for healthy cognitive aging.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonathan G HakunDepartment of Neurology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.ORCID 0000-0003-3389-7136
Lizbeth BensonInstitute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Tian QiuDepartment of Public Health Sciences, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
Daniel B ElbichDepartment of Neurology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
Mindy KatzDepartment of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.
Pamela A ShawDivision of Biostatistics, Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Martin J SliwinskiDepartment of Public Health Sciences, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.ORCID 0000-0002-9611-7558
Yasmin Mossavar-RahmaniDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.

Funding

Ambulatory Methods for Measuring Cognitive ChangeU2CAG060408 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI SLIWINSKI, MARTIN J · 2018 to 2022
$14.9M
Multicultural Healthy Diet to Reduce Cognitive Decline & Alzheimer Disease RiskR01AG055527 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI MOSSAVAR-RAHMANI, YASMIN · 2017 to 2022
$4.7M
Mechanisms of Adherence to Light Intensity Physical Activity to Prevent Alzheimer's Disease and Related DementiasR33AG078084 · NIA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Jonathan G. Hakun, CHRISTOPHER N. SCIAMANNA · 2023 to 2026
$3.1M
Self-regulation of Health Promotion: the Roles of Momentary Variability in Working Memory Capacity and Neurocognitive AgingR00AG056670 · NIA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI HAKUN, JONATHAN G. · 2019 to 2021
$721k
Novel Approaches to Monitor the Safety and Effectiveness of Newly Marketed Diabetes Medications in Older Adults Considering Frailty and MultimorbidityK08AG055670 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI PATORNO, ELISABETTA · 2018 to 2021
$661k
Mechanisms of Adherence to Light Intensity Physical Activity to Prevent Alzheimer's Disease and Related DementiasR61AG078084 · NIA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI HAKUN, JONATHAN G. · 2022 to 2022
$371k
Self-regulation of Health Promotion: the Roles of Momentary Variability in Working Memory Capacity and Neurocognitive AgingK99AG056670 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI HAKUN, JONATHAN G. · 2017 to 2018
$201k
NIA NIH HHS K08 AG055670NIA NIH HHS K99 AG056670NIA NIH HHS R00 AG056670NIA NIH HHS R01 AG055527NIA NIH HHS R33 AG078084NIA NIH HHS R61 AG078084NIA NIH HHS U2C AG060408NIH HHS R01AG055527
6 · The paper itself

Abstract

backgroundPhysical activity has been associated with a wide range of health benefits including long-term benefits for cognitive and brain health. Whether episodes of everyday physical activity are associated with immediate cognitive benefits remains unknown. PURPOSE: The purpose of the current study was to examine whether episodes of physical activity, occurring over the course of participants' daily lives, are associated with short-term improvements in cognitive health.

methodsParticipants completed a 9-day ecological momentary assessment protocol involving 5 daily assessments of self-reported physical activity and ambulatory cognitive assessments of processing speed and visuospatial working memory. Data were analyzed in a multilevel modeling framework to explore changes in performance on each task associated with physical activity during the period leading up to the assessment as well as individual differences in average frequency of physical activity.

resultsResults of MLMs indicated that engaging in physical activity during the period (~3.5 hr) leading up to an assessment was associated with improvements in processing speed equivalent to 4 years of cognitive aging. Such improvements were observed for both light and moderate-to-vigorous physical activity levels. No association was observed for visuospatial working memory accuracy; however, response time during the working memory task reliably mirrored the association observed for processing speed. The short-term benefits were observed, particularly, for individuals with an overall higher frequency of reported physical activity.

conclusionsOur findings suggest that engaging in everyday physical activity of any intensity level may have short-term, acute benefits for cognitive health and point to new potential targets for intervention. CLINICAL TRIAL INFORMATION: NCT03240406.

Indexed as

CognitionCognitive AgingExerciseMemory, Short-TermAdultEcological Momentary AssessmentFemaleHumansMaleMiddle AgedAmbulatory assessmentCognitionEMAPhysical activity

Identifiers

PMID39427230
PMCPMC11783295

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.