ArticleBMC geriatrics2024
Association of preoperative cognitive frailty with postoperative complications in older patients under general anesthesia: a prospective cohort study.
Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The predictive value of multidimensional frailty instruments for postoperative adverse outcomes in cancer patients: a systematic review and meta-analysis.World journal of surgical oncology · 2026Pooled it
- Preoperative Hemoglobin Decline in Older Hip Fracture Patients: Beyond Mortality and Fixed Thresholds.Geriatrics & gerontology international · 2026Article
- Cardiac Rehabilitation and Cognitive Impairment: Elective Affinities or Fatal Attraction.Journal of clinical medicine · 2026Review
- Preoperative Cognitive Function and Physical Frailty Predict Decision Satisfaction and Postoperative Adherence in Older Gynecologic Oncology Patients: A Prospective Observational Study.Current oncology (Toronto, Ont.) · 2026Observational
- Cognitive Impact of Colorectal Cancer Surgery in Elderly Patients: A Narrative Review.Cancers · 2026Review
- Prevalence and predictive factors of cognitive impairment among hospitalized older adults in iran: a cross-sectional study, 2024.Aging clinical and experimental research · 2026Article
- Impact of Preoperative Frailty on Postoperative Complications and Cognitive Impairment in Liver Cancer Patients: An Observational Cohort Study.Clinical interventions in aging · 2026Observational
- Leveraging transformer-based artificial intelligence for enhanced anesthetic decision-making in orthopedic surgery.Frontiers in medicine · 2026Article
- Correlation between frailty status and prolonged length of stay in the post-anesthesia care unit and development of a predictive model in elderly patients undergoing painless gastrointestinal endoscopy.Frontiers in medicine · 2026Article
- Preoperative Anesthesia Assessment in Elderly Patients: Challenges and Opportunities for Safer Perioperative Care.Cureus · 2025Review
- Impact of Physical and Cognitive Frailty on Long-Term Mortality in Older Patients undergoing Elective Non-cardiac Surgery.Annals of geriatric medicine and research · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
backgroundCognitive frailty (CF) is characterized by the coexistence of physical frailty and cognitive impairment, and it is associated with adverse health outcomes. Older adults are particularly vulnerable to CF due to factors such as age-related brain changes and the presence of comorbidities.
objectiveTo investigate the effect of preoperative CF on postoperative complications in older patients.
methodsThis prospective cohort study was conducted among 253 patients aged 60-85 years, who underwent elective orthopedic and abdominal surgery (with a postoperative hospital stay of ≥ 3 days) at the Second Affiliated Hospital of Guangzhou University of Chinese Medicine from May 2023 to November 2023. CF was assessed using the Montreal Cognitive Assessment (MoCA) for the cognitive status and the Fried criteria for five frailty scales. Participants were split into four groups: Group A (neither frailty nor cognitive impairment), Group B (frailty without cognitive impairment), Group C (cognitive impairment without frailty), and Group D (cognitive frailty). The primary outcome was postoperative complications, while secondary outcomes included mobility disability, prolonged hospital stay (PLOS), re-operation and 90-day readmission.
resultsThe median age (interquartile range) of participants was 69 (65-73) years, of which 40.3% were male. The prevalence of CF was 17.8%. The incidence of postoperative complications was 18.2% in Group A, 50.0% in Group B, 37.4% in Group C, and 75.6% in Group D. Multivariate analysis revealed that, compared to the control group (without cognitive impairment or frailty), patients with CF had a significantly higher risk of postoperative complications (OR, 12.86; 95%CI, 4.23-39.08). "Patients with frailty without cognitive impairment" had an increased risk (OR, 6.53; 95%CI, 2.04-20.9), while "those with cognitive impairment without frailty" also showed a higher risk (OR, 3.46; 95%CI, 1.57-7.64).
conclusionsCognitive frailty is significantly associated with an increased risk of postoperative adverse outcomes in older patients undergoing orthopedic and abdominal surgeries with general anesthesia. It indicates that clinicians should pay much attention to these older adults with CF.
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