Evidence map›Paper›PMID 39427096›Full record

ArticleScientific reports2024

Study on sentinel hosts for surveillance of future COVID-19-like outbreaks.

Yanjiao Li, Jingjing Hu, Jingjing Hou, Shuiping Lu, Jiasheng Xiong, Yuxi Wang, Zhong Sun, Weijie Chen, Yue Pan, Karuppiah Thilakavathy and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yanjiao Li *Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200433, China.
Jingjing Hu *Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200433, China.
Jingjing Hou *Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China.
Shuiping Lu *Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200433, China.
Jiasheng XiongDivision of Emergency Management, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, 200336, China.
Yuxi WangDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, 200433, China.
Zhong SunDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, 43400, Malaysia.
Weijie ChenDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, 200433, China.
Yue PanDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, 200433, China.
Karuppiah ThilakavathyDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, 43400, Malaysia.
Yi FengDepartment of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Qingwu JiangDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, 200433, China.
Weibing WangDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, 200433, China. wwb@fudan.edu.cn.
Chenglong XiongDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, 200433, China. xiongchenglong@fudan.edu.cn.

Funding

the National Natural Science Foundation of China 81872673the Shanghai New Three-year Action Plan for Public Health GWVI-11.1-03the Three-Year Action Plan of Shanghai Public Health System Construction-Key Discipline Construction GWV-10.1-XK03
6 · The paper itself

Abstract

The spread of SARS-CoV-2 to animals has the potential to evolve independently. In this study, we distinguished several sentinel animal species and genera for monitoring the re-emergence of COVID-19 or the new outbreak of COVID-19-like disease. We analyzed SARS-CoV-2 genomic data from human and nonhuman mammals in the taxonomic hierarchies of species, genus, family and order of their host. We find that SARS-CoV-2 carried by domestic dog (Canis lupus familiaris), domestic cat (Felis catus), mink (Neovison vison), and white-tailed deer (Odocoileus virginianus) cluster closely to human-origin viruses and show no differences in the majority of amino acids, but have the most positively selected sites and should be monitored to prevent the re-emergence of COVID-19 caused by novel variants of SARS-CoV-2. Viruses from the genera Panthera (especially lion (Panthera leo)), Manis and Rhinolophus differ significantly from human-origin viruses, and long-term surveillance should be undertaken to prevent the future COVID-19-like outbreaks. Investigation of the variation dynamics of sites 142, 501, 655, 681 and 950 within the S protein may be necessary to predict the novel animal SARS-CoV-2 variants.

Indexed as

COVID-19Disease OutbreaksSARS-CoV-2AnimalsCatsDogsGenome, ViralHumansMinkPhylogenySentinel SpeciesAmino acid polymorphismPhylogenetic treePositively selected siteSARS-CoV-2Sentinel hostSpike protein

Identifiers

PMID39427096
PMCPMC11490639

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.