Evidence map›Paper›PMID 39426987›Full record

ArticleScientific reports2024

Higher CALLY index levels indicate lower sarcopenia risk among middle-aged and elderly community residents as well as hospitalized patients.

Yijing Li, Qiaoxin Wei, Xinlong Ke, Yihui Xu, Bingqing Xu, Kaiyu Zhang, Wenyu Zhu, Xiaoyi Lian, Lei Liu, Zhengli Guo

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In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yijing LiTongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Qiaoxin WeiDepartment of Oncology, Beijing You'an Hospital, Capital Medical University, Beijing, 100069, China.
Xinlong KeDepartment of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, China.
Yihui XuDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, Jiangsu, China.
Bingqing XuDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, Jiangsu, China.
Kaiyu ZhangDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, Jiangsu, China.
Wenyu ZhuDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, Jiangsu, China.
Xiaoyi LianDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, Jiangsu, China.
Lei LiuDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, Jiangsu, China.
Zhengli GuoDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, Jiangsu, China. 350834416@qq.com.

Funding

Early Sarcopenia Screening and Intervention Research in the Elderly Population of the Community (Suzhou Municipal Health Commission Science and Technology Project No. LCZX201911Epidemiological Investigation and Intervention Strategy Research on Geriatric Syndrome (GS) in Kunshan Area No. KSF202129Study on Sarcopenia Screening and Evaluation of Internal Capacity of Elderly People in the Community No. KS2205
6 · The paper itself

Abstract

The C-reactive protein-albumin-lymphocyte (CALLY) index, which integrates albumin, lymphocytes, and C-reactive protein levels, has emerged as a novel method to assess nutritional and inflammatory statuses in patients. This study examined the correlation between the CALLY index and sarcopenia risk using two cohorts: 1804 community dwellers from the NHANES database in the United States and 139 patients from the Department of Gerontology at Kunshan Hospital, China. In the US community cohort, RCS curve analysis was used to examine the non-linear relationship between inflammatory/nutritional markers and sarcopenia, subgroup analysis was also conducted. Logistic regression was employed to evaluate the association between the CALLY index and the risk of sarcopenia in both cohorts. Results demonstrated a significant non-linear relationship between the CALLY index and the risk of sarcopenia (P < 0.001). Elevated levels of the CALLY index are independently linked to a decreased risk of sarcopenia in both community residents (OR = 0.35, 95% CI 0.20-0.57, Q3 CALLY index and OR = 0.26, 95% CI 0.11-0.56, Q4 CALLY index) and hospitalized patients (OR = 0.35, 95% CI 0.12-0.96). This finding identified low CALLY index as a conveniently measurable parameter, serving as a nutritional and inflammatory risk factor for sarcopenia.

Indexed as

C-Reactive ProteinSarcopeniaAgedAged, 80 and overBiomarkersChinaFemaleHospitalizationHumansLymphocyte CountMaleMiddle AgedNutritional StatusRisk FactorsSerum AlbuminUnited StatesBiomarkersC-Reactive ProteinSerum AlbuminCRP-albumin-lymphocyte (CALLY) indexInflammationNutritionSarcopenia

Identifiers

PMID39426987
PMCPMC11490578

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.