Evidence map›Paper›PMID 39426950›Full record

ArticleNature communications2024

ASI-RIM neuronal axis regulates systemic mitochondrial stress response via TGF-β signaling cascade.

Zihao Wang, Qian Zhang, Yayun Jiang, Jun Zhou, Ye Tian

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zihao Wang *State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101, Beijing, China.ORCID 0000-0003-0135-505X
Qian Zhang *State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101, Beijing, China.ORCID 0000-0003-1188-8335
Yayun JiangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101, Beijing, China.
Jun ZhouState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101, Beijing, China.ORCID 0000-0002-8193-554X
Ye TianState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101, Beijing, China. ytian@genetics.ac.cn.ORCID 0000-0002-7675-9270

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
National Natural Science Foundation of China (National Science Foundation of China) 31930023National Natural Science Foundation of China (National Science Foundation of China) 32200624National Natural Science Foundation of China (National Science Foundation of China) 32225025National Natural Science Foundation of China (National Science Foundation of China) 32321004National Natural Science Foundation of China (National Science Foundation of China) 32471212National Natural Science Foundation of China (National Science Foundation of China) 92254305NIH HHS P40 OD010440
6 · The paper itself

Abstract

Morphogens play a critical role in coordinating stress adaptation and aging across tissues, yet their involvement in neuronal mitochondrial stress responses and systemic effects remains unclear. In this study, we reveal that the transforming growth factor beta (TGF-β) DAF-7 is pivotal in mediating the intestinal mitochondrial unfolded protein response (UPR

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsMitochondriaSignal TransductionStress, PhysiologicalTransforming Growth Factor betaUnfolded Protein ResponseAnimalsDopaminegamma-Aminobutyric AcidInterneuronsLongevityNeuronsReceptors, Transforming Growth Factor betaSensory Receptor CellsCaenorhabditis elegans ProteinsDAF-7 protein, C elegansDopaminegamma-Aminobutyric AcidReceptors, Transforming Growth Factor betaTransforming Growth Factor beta

Identifiers

PMID39426950
PMCPMC11490647

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.