Evidence map›Paper›PMID 39426624›Full record

Trial reportAmerican journal of obstetrics & gynecology MFM2024

Antihypertensive therapy and unplanned maternal postpartum healthcare utilization in patients with mild chronic hypertension.

Anna Palatnik, Justin Leach, Lorie Harper, Baha Sibai, Sherri Longo, Lorraine Dugoff, Kirsten Lawrence, Brenna L Hughes, Joseph Bell, Rodney K Edwards and 27 more

Abstract readMulticenter StudyRandomized Controlled TrialPragmatic Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of obstetrics & gynecology MFM, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Anna PalatnikDepartment of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI (Palatnik). Electronic address: apalatnik@mcw.edu.
Justin LeachDepartment of Biostatistics, University of Alabama at Birmingham (Leach), Birmingham, Alabama, USA.
Lorie HarperDepartment of Women's Health, University of Texas at Austin (Harper), Austin, Texas, USA.
Baha SibaiDepartment of Obstetrics and Gynecology, University of Texas at Houston (Sibai), Houston, Texas, USA.
Sherri LongoOchsner Baptist Medical Center (Longo), New Orleans, LA, USA.
Lorraine DugoffDepartment of Obstetrics and Gynecology, University of Pennsylvania (Dugoff), Philadelphia, Pennsylvania, USA.
Kirsten LawrenceDepartment of Obstetrics and Gynecology, Columbia University (Lawrence), New York, NY, USA.
Brenna L HughesDepartment of Obstetrics and Gynecology, Duke University (Hughes), Durham, NC, USA.
Joseph BellSt. Luke's University Health Network (Bell), Bethlehem, PA, USA.
Rodney K EdwardsDepartment of Obstetrics and Gynecology, University of Oklahoma Health Sciences (Edwards), Oklahoma city, OK, USA.
Kelly S GibsonMetroHealth System (Gibson), Cleveland, OH, USA.
Caroline RouseDepartment of Obstetrics and Gynecology, Indiana University (Rouse), Indianapolis, IN, USA.
Lauren PlanteDepartment of Obstetrics and Gynecology, Drexel University College of Medicine (Plante), Philadelphia, PA, USA.
Kara K HoppeDepartment of Obstetrics and Gynecology, UnityPoint Health-Meriter Hospital/Marshfield Clinic (Hoppe), Madison, WI, USA.
Janelle ForoutanSt. Peters University Hospital (Foroutan), New Brunswick, NJ, USA.
Methodius TuuliDepartment of Obstetrics and Gynecology, Brown University (Tuuli), Providence, RI, USA.
Hyagriv N SimhanDepartment of Obstetrics and Gynecology, Magee Women's Hospital and University of Pittsburgh (Simhan), Pittsburgh, PA, USA.
Heather FreyDepartment of Obstetrics and Gynecology, Ohio State University (Frey), Columbus, Ohio, USA.
Todd RosenDepartment of Obstetrics and Gynecology, Rutgers University-Robert Wood Johnson Medical School (Rosen), New Brunswick, NJ, USA.
Torri D MetzDepartment of Obstetrics and Gynecology, University of Utah (Metz), Salt Lake City, UT, USA.
Susan BakerDepartment of Obstetrics and Gynecology, University of South Alabama at Mobile (Baker), Mobile, AL, USA.
Wendy KinzlerDepartment of Obstetrics and Gynecology, NYU Langone Hospital-Long Island (Kinzler), New York, NY, USA.
Emily J SuDepartment of Obstetrics and Gynecology, University of Colorado (Su), Aurora, CO, USA.
Iris KrishnaDepartment of Obstetrics and Gynecology, Emory University (Krishna), Atlanta GA, USA.
Mary E NortonDepartment of Obstetrics and Gynecology, University of California San Francisco; Zuckerberg San Francisco General Hospital (Norton), San Francisco, California, USA.
Daniel SkupskiDepartment of Obstetrics and Gynecology, New York Presbyterian Queens Hospital (Skupski), New York, NY, USA.
Yasser Y El-SayedDepartment of Obstetrics and Gynecology, Stanford University (El-Sayed), Stanford, CA, USA.
Leonardo PereiraOregon Health and Science University, Portland, Oregon (Pereira).
Everett F MagannDepartment of Obstetrics, University of Arkansas for Medical Sciences, Little Rock, AR (Magann).
Mounira HabliFetal Care Center of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH (Habli).
Nancy L GellerOffice of Biostatistics Research, NHLBI (Geller), Bethesda, MD, USA.
Shauna WilliamsDepartment of Obstetrics, Gynecology and Women's Health, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, NJ (Williams).
David S McKennaDepartment of Obstetrics and Gynecology, Wright State University and Miami Valley Hospital, Dayton, OH (McKenna).
Eugene ChangMedical University of South Carolina, Charleston, SC (Chang).
Joanne QuiñonesDepartment of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Lehigh Valley Health Network, Allentown, PA (Quiñones).
Jeff M SzychowskiDepartment of Biostatistics and Center for Women's Reproductive Health, University of Alabama at Birmingham (Szychowski), Birmingham, Alabama, USA.
Alan T N TitaDepartment of Obstetrics and Gynecology and Center for Women's Reproductive Health, University of Alabama at Birmingham (Tita), Birmingham , Alabama, USA.

Funding

Chronic Hypertension and Pregnancy-CHAP Clinical Coordinating CenterU01HL120338 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TITA, ALAN THEVENET N. · 2014 to 2020
$16.5M
Intensive postpartum antihypertensive treatment to improve women's cardiovascular healthR34HL165013 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI PALATNIK, ANNA · 2023 to 2025
$648k
NHLBI NIH HHS R34 HL165013NHLBI NIH HHS U01 HL120338
6 · The paper itself

Abstract

objectiveTo test whether treatment of mild chronic hypertension (CHTN) in pregnancy is associated with lower rates of unplanned maternal healthcare utilization postpartum.

methodsThis was a secondary analysis of the CHTN and pregnancy study, a prospective, open-label, pragmatic, multicenter, randomized treatment trial of pregnant people with mild CHTN. All patients with a postpartum follow-up assessment were included. The primary outcome was unplanned healthcare utilization, defined as unplanned postpartum clinic visits, Emergency Department (ED) or triage visits, or unplanned hospital admissions within 6 weeks postpartum. Differences in outcomes were compared between study groups (Active Group: blood pressure goal of<140/90 mm Hg, and Control Group: blood pressure goal of <160/105 mm Hg), and factors associated with outcomes were examined using logistic regression.

resultsA total of 2293 patients were included with 1157 (50.5%) in the active group and 1136 (49.5%) in the control group. Rates of unplanned maternal postpartum healthcare utilization did not differ between treatment and control groups, (20.2% vs 23.3%, P=.07, aOR 0.84, 95% CI 0.69-1.03). However, ED or triage/maternity evaluation unit visits were significantly lower in the Active group (10.2% vs 13.2%, P=.03, aOR 0.76, 95% 0.58-0.99). Higher BMI at enrollment and cesarean delivery were associated with higher odds of unplanned postpartum healthcare utilization.

conclusionWhile treatment of mild CHTN during pregnancy and postpartum was not significantly associated with overall unplanned healthcare resource utilization, it was associated with lower rates of postpartum ED and triage visits.

Indexed as

Antihypertensive AgentsHypertensionAdultChronic DiseaseEmergency Service, HospitalFemaleHospitalizationHumansPatient Acceptance of Health CarePostpartum PeriodPregnancyPregnancy Complications, CardiovascularProspective StudiesTriageAntihypertensive Agentsantihypertensive treatmentEmergency Department visitshypertensionmild chronic hypertensionreadmissionunplanned healthcare utilization

Identifiers

PMID39426624
PMCPMC11663106

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.