Evidence map›Paper›PMID 39425867›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

One-year trajectories of physical and mental health-related quality of life, fatigue and dyspnoea in COVID-19 survivors.

Gerko Schaap, John F Davelaar, Peter M Ten Klooster, Carine J M Doggen, Job van der Palen, Christina Bode, Harald E Vonkeman

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Gerko SchaapSection of Psychology, Health & Technology, University of Twente, Enschede, The Netherlands. g.schaap@utwente.nl.ORCID http://orcid.org/0000-0003-4710-2971
John F DavelaarSection of Psychology, Health & Technology, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0003-4242-2589
Peter M Ten KloosterSection of Psychology, Health & Technology, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0002-2565-5439
Carine J M DoggenSection of Health Technology and Services Research, Technical Medical Centre, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0003-4766-4333
Job van der PalenSection of Cognition, Data and Education, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0003-1071-6769
Christina BodeSection of Psychology, Health & Technology, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0002-1641-8028
Harald E VonkemanSection of Psychology, Health & Technology, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0003-3792-7718

Funding

Fondation Vrienden van MST Fondation Vrienden van MST
6 · The paper itself

Abstract

purposeA substantial number of people experience a persisting impact on health-related quality of life (HRQoL) after COVID-19. The current study aims to identify different trajectories of physical and mental HRQoL, fatigue severity, and dyspnoea severity following hospitalisation with COVID-19, and associated factors of these trajectories.

methods500 patients with COVID-19 were followed for one year in a longitudinal cohort study. Self-reported outcomes were measured at 3, 6, 9, and 12 months after hospitalisation. Distinct trajectories were characterised using Growth Mixture Modelling. Sociodemographic and clinical correlates of trajectories were investigated using multivariable (multinomial) logistic regression analyses.

resultsThree trajectories ('stable high' (16%), 'improving' (40%), and 'stable low' (44%)) were found for physical HRQoL, and four ('stable high' (43%), 'improving' (14%), 'middle declining' (17%), and 'low' (26%)) for mental HRQoL. Older age, overweight and obesity, lower education, and comorbidities were associated with 'low' physical HRQoL. Younger age was associated with 'low' mental HRQoL. Four fatigue trajectories ('no fatigue' (15%), 'improving' (40%), 'low-severe' (27%), and 'high-severe' (18%)) were found. Participants either experienced almost never ('no dyspnoea', 75%) or almost always ('severe', 25%) dyspnoea. High co-occurrences between low HRQoL and severe fatigue and dyspnoea symptom trajectories were found.

conclusionA substantial number of COVID-19 survivors continue to struggle with reduced HRQoL over time. However, large variations in these physical and mental HRQoL trajectories exist, and trajectories are associated with persisting COVID-19-related symptoms or pre-hospitalised health status. Regular measurement of HRQoL and post-COVID symptoms may help identify those that may benefit from timely interventions.

Indexed as

COVID-19DyspneaFatigueMental HealthQuality of LifeSurvivorsAdultAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedSARS-CoV-2Severity of Illness IndexCOVID-19DyspnoeaFatigueLatent class growth mixture modellingPost-COVID-19 syndromeQuality of life

Identifiers

PMID39425867
PMCPMC11865161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.