SynthesisBMC pregnancy and childbirth2024
The association between maternal anemia and neonatal anemia: a systematic review and meta-analysis.
Synthesis in BMC pregnancy and childbirth, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Modifiable risk factors for anemia in pregnancy: an umbrella review of systematic reviews and meta-analyses.BMC pregnancy and childbirth · 2025Pooled it
- Trial
- The influence of maternal anemia on neonatal neurodevelopment: a systematic review and meta-analysis.Asian biomedicine : research, reviews and news · 2026Article
- Prevalence, Morphological Types, and Associated Factors of Neonatal Anemia at a Rural Referral Hospital, Uganda.Journal of blood medicine · 2026Article
- Maternal and infant outcomes of pregnancy anemia at one month postpartum: a cohort analysis.BMC pregnancy and childbirth · 2025Article
- The Compounded Risk of Maternal Anemia and Preeclampsia: Neonatal Outcomes and Predictive Modeling in a Low-Resource Tertiary Center.Journal of clinical medicine · 2025Article
- Article
- Prevalence and associated factors of at risk of anemia among children under five in Northeast Thailand using noninvasive hemoglobin screening in a cross sectional study.Scientific reports · 2025Article
- Characteristics of Anemia in Children Aged 6 Months to 5 Years Attending External Consultations at a Pediatric Hospital in Lisbon, Portugal.Children (Basel, Switzerland) · 2025Article
- Predicting Risk for Patent Ductus Arteriosus in the Neonate: A Machine Learning Analysis.Medicina (Kaunas, Lithuania) · 2025Article
- Providers' Practices and Associated Factors in Educating Pregnant Women on the Prevention of Maternal Anemia During Antenatal Care Visits in Ujiji Municipality, Kigoma Region, Tanzania.Healthcare (Basel, Switzerland) · 2025Article
- Detection of postpartum women anemia and its impact on their offspring in Zhejiang Province, China.Frontiers in nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
importanceNeonatal anemia has a long-term effect on children's growth and development. Anemia during pregnancy is also the most widespread nutritional deficiency among pregnant women in the world; If it leads to anemia in newborns, it will affect a wide range of people and be a public health problem worthy of attention.
objectiveTo study the relationship between maternal anemia during pregnancy and neonatal hemoglobin levels. DATA SOURCES: PubMed, Web of science, Scopus, MEDLINE, Embase, ProQuest, Dissertations & Theses Global, The Cochrane Library, China Biology Medicine Database, Chinese CNKI Database, and Chinese Wanfang Database were systematically searched from inception to August 31, 2022. STUDY SELECTION: The meta-analysis included all original studies which pertain to cohort studies, case-control studies or cross-sectional studies that investigated the relationship between maternal anemia during pregnancy and neonatal hemoglobin levels. DATA EXTRACTION AND SYNTHESIS: Hemoglobin level of both anemic and non-anemic pregnant mothers and their paired newborns were pooled from the selected studies. The random-effects model was used to assess the risk of getting a lower neonatal hemoglobin level between mothers with and without pregnant anemia. Data analyses were performed from September 5, 2022, to March 10, 2023. MAIN OUTCOMES AND MEASURES: Maternal anemia during pregnancy is a risk factor of lower neonatal hemoglobin levels.
resultsThe initial search yielded 4267 records of which 116 articles underwent full-text evaluation, which identified 18 articles and a total of 1873 patients that were included. The findings of the meta-analysis showed a significant difference between the two groups(MD=-1.38; 95%CI:[-1.96,-0.80]. p<0.01), while the co-effect showed that the neonatal hemoglobin value of anemic mothers was 1.38g/dL lower than that of non-anemic mothers(-1.96,-0.80), suggesting a correlation between maternal anemia lower neonatal hemoglobin levels. CONCLUSIONS AND RELEVANCE: This systematic review and meta-analysis demonstrated that maternal anemia during pregnancy were associated with a lower level of newborn hemoglobin levels. This may enable a better understanding of neonatal anemia and provide guidance towards future development of nutritional supplementation during pregnancy and the prediction of postpartum outcomes.
trial registrationPROSPERO Identifier: CRD42022352759.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.