Evidence map›Paper›PMID 39425026›Full record

ArticleBMC nephrology2024

Successful prevention of BK-polyomavirus nephropathy using extracorporeal photopheresis for immunosuppression minimisation following severe BK polyomavirus replication after kidney transplantation in a double lung transplant recipient, a case report.

Florent Von Tokarski, François Parquin, Antoine Roux, Victor Hayem, Thibault Kerdiles, Marion Rabant, Pierre Isnard, Alexandre Loupy, Cyril Fourniol, Leila Tricot and 3 more

Abstract readCase Reports
In one paragraph

Article in BMC nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. BK Polyomavirus-associated nephropathy - diagnostic and treatment standard.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Florent Von TokarskiFaculty of Medical School, University of Versailles-Saint-Quentin-en-Yvelines, Montigny-Le-Bretonneux, France. f.von-tokarski@hopital-foch.com.
François ParquinDepartment of Pneumology, Adult Cystic Fibrosis Center and Lung Transplantation Dept, Foch Hospital, Suresnes, France.
Antoine RouxFaculty of Medical School, University of Versailles-Saint-Quentin-en-Yvelines, Montigny-Le-Bretonneux, France.
Victor HayemDepartment of Nephrology, Dialysis, and Transplantation, Foch Hospital, Suresnes, France.
Thibault KerdilesDepartment of Nephrology, Dialysis, and Transplantation, Foch Hospital, Suresnes, France.
Marion RabantDepartment of Pathology, APHP, Necker Hospital, Université Paris Cité, Paris, France.
Pierre IsnardDepartment of Pathology, APHP, Necker Hospital, Université Paris Cité, Paris, France.
Alexandre LoupyParis Transplant Group, National Institute of Health and Medical Research, PARCC U970, Paris, France.
Cyril FourniolDepartment of Urology, Foch Hospital, Foch Hospital, Suresnes, France.
Leila TricotDepartment of Nephrology, Dialysis, and Transplantation, Foch Hospital, Suresnes, France.
Clément PicardDepartment of Pneumology, Adult Cystic Fibrosis Center and Lung Transplantation Dept, Foch Hospital, Suresnes, France.
Alexandre HertigFaculty of Medical School, University of Versailles-Saint-Quentin-en-Yvelines, Montigny-Le-Bretonneux, France.
Julie OniszczukDepartment of Nephrology, Dialysis, and Transplantation, Foch Hospital, Suresnes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBK-polyomavirus (BKpyV) nephropathy (BKVN) is associated with end-stage kidney disease in kidney and non-kidney solid organ transplantation, with no curative treatment. CASE PRESENTATION: A 45-year-old woman with a past medical history of double lung transplantation subsequently developed end-stage kidney disease, of undetermined origin. One month after receiving a kidney transplant, a diagnosis of early BKVN was suspected, and in retrospect was a reasonable cause for the loss of her native kidneys. Minimisation of immunosuppression, achieved through extracorporeal photopheresis, allowed clearance of BKpyV and so prevented nephropathy. Both lung and kidney grafts had a satisfactory and stable function after one year of follow-up, with no rejection.

conclusionsExtracorporeal photopheresis may have facilitated minimisation of immunosuppression and BKpyV clearance without lung allograft rejection.

Indexed as

BK VirusKidney TransplantationLung TransplantationPhotopheresisPolyomavirus InfectionsTumor Virus InfectionsFemaleHumansImmunosuppression TherapyKidney DiseasesKidney Failure, ChronicMiddle AgedPostoperative ComplicationsVirus ReplicationBK-polyomavirusCase reportExtracorporeal photopheresisKidney transplantLung transplantMinimization

Identifiers

PMID39425026
PMCPMC11490108

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.