Evidence map›Paper›PMID 39424914›Full record

ArticleEye (London, England)2025

Recurrent retinal detachment in Stickler Syndrome.

Timothy H Chen, Marjan Imani Fooladi, Michelle Alabek, Hannah L Scanga, Kelly S Tripi, Ken K Nischal, Joseph N Martel

Abstract read
In one paragraph

Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Outcomes of surgical intervention in retinal detachment in stickler syndrome: a systematic review and meta analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Timothy H ChenDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA. timothyhschen@gmail.com.ORCID 0009-0004-8227-6808
Marjan Imani FooladiDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Michelle AlabekDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Hannah L ScangaDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Kelly S TripiDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Ken K NischalDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-5616-5275
Joseph N MartelDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

Virus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ethan A Rossi · 1989 to 2026
$17.8M
NEI NIH HHS P30 EY008098U.S. Department of Health & Human Services | National Institutes of Health (NIH) P30 EY08098
6 · The paper itself

Abstract

objectiveTo assess clinical factors leading to recurrent retinal detachment (RD) and characteristics of recurrence in patients with Stickler Syndrome.

methodsRetrospective case series study of patients with clinical diagnosis of Stickler Syndrome who underwent rhegmatogenous RD repair. Recurrent RD after initial surgery was categorized as "early" if the recurrence was within 1 year or "late" if greater than 1 year.

resultsThirty eyes from 22 patients underwent rhegmatogenous RD repair. For initial repair, 13 eyes underwent pars plana vitrectomy combined with scleral buckling (PPV/SB), 16 eyes underwent primary scleral buckling (SB), and 1 eye underwent pneumatic retinopexy (PnR). Recurrent RD occurred in 6 (46%) PPV/SB eyes (5 early and 1 late), 10 (63%) SB eyes (3 early and 7 late), and 0 (0%) PnR eyes (p = 0.61). PPV/SB was preferred for eyes presenting with total detachment (82%), giant retinal tears (100%), and proliferative vitreoretinopathy (PVR) (80%). For eyes with early recurrent RD, 6 (75%) had PVR leading to recurrence. For eyes with late recurrent RD, 7 (87.5%) developed a new retinal break leading to recurrence, including 4 with a break posterior to the buckle indentation apex. At last follow-up, median LogMAR visual acuity was 0.68 for eyes with recurrent RD compared to 0.29 for eyes without recurrence (p = 0.27).

conclusionsEarly recurrent RD was mostly caused by PVR, while late recurrent RD was mostly due to new retinal breaks. Eyes with seemingly uncomplicated rhegmatogenous RD repair with primary SB remained at high risk for late re-detachment.

Indexed as

ArthritisConnective Tissue DiseasesHearing Loss, SensorineuralRetinal DetachmentAdolescentAdultAgedChildFemaleHumansMaleMiddle AgedRecurrenceRetrospective StudiesScleral BucklingVisual Acuity

Identifiers

PMID39424914
PMCPMC11733170

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.