Evidence map›Paper›PMID 39424852›Full record

ArticleScientific reports2024

Exploring the dynamics of HIV and CD4

Meshal Shutaywi, Zahir Shah, Narcisa Vrinceanu, Rashid Jan, Wejdan Deebani

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Meshal ShutaywiDepartment of Mathematics, College of Science and Arts, King Abdulaziz University, P.O. Box 344, 21911, Rabigh, Saudi Arabia.
Zahir ShahDepartment of Mathematical Sciences, University of Lakki Marwat, Lakki Marwat, KPK, 28420, Pakistan. zahir@ulm.edu.pk.
Narcisa VrinceanuFaculty of Engineering, Department of Industrial Machines and Equipments, "Lucian Blaga" University of Sibiu, 10 Victoriei Boulevard, Sibiu, Romania. vrinceanu.narcisai@ulbsibiu.ro.
Rashid JanDepartment of Civil Engineering, Institute of Energy Infrastructure (IEI), College of Engineering, Universiti Tenaga Nasional (UNITEN), Putrajaya Campus, Jalan IKRAM-UNITEN, 43000, Kajang, Selangor, Malaysia.
Wejdan DeebaniDepartment of Mathematics, College of Science and Arts, King Abdulaziz University, P.O. Box 344, 21911, Rabigh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is important to examine and comprehend how HIV interacts with the immune system in order to manage the infection, enhance patient outcomes, advance medical research, and support global health and socioeconomic stability. In this study, we formulate the dynamics of HIV infection to investigate the intricate interactions between HIV and [Formula: see text] T-cells. The Atangana-Baleanu and Caputo-Fabrizio derivative frameworks are applied to comprehensively examine the phenomenon of HIV viral transmission. The basic concepts and results of fractional calculus are presented for the analysis of the model. In our work, we focus on the dynamical behavior of HIV and immune system. We introduce numerical schemes to elucidate the solution pathways of the recommended system of HIV. We have shown the influence of various input factors on the solution pathways of the recommended fractional system and highlighted the oscillatory behavior and chaotic nature of the dynamics. Our findings demonstrate the complexity of the system under study by revealing the existence of the chaotic and oscillatory nature in the dynamics of HIV. In order to quantitatively characterize HIV dynamics, a number of simulations are carried out, providing a visual representation of the effects of different input variables. It has been observed that the chaos and the oscillatory behaviour is strongly related to the nonlinearity of the system. The present study provides a basis for further initiatives that try to enhance interventions and policies to lessen the worldwide burden of infection.

Indexed as

CD4-Positive T-LymphocytesHIV InfectionsComputer SimulationHumansFractional-calculusHIV infectionMathematical modelNumerical methodSolution pathways

Identifiers

PMID39424852
PMCPMC11489594

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.