Evidence map›Paper›PMID 39424428›Full record

ArticleJournal of the American Heart Association2024

Association of Prepregnancy Cardiometabolic Health With Hypertensive Disorders of Pregnancy Among Historically Underrepresented Groups in the United States.

Yaa A Kwapong, Theresa Boyer, Oluwalonimi Adebowale, S Michelle Ogunwole, Arthur Jason Vaught, Chiadi E Ndumele, Allison G Hays, Roger S Blumenthal, Erin D Michos, Elizabeth Selvin and 2 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yaa A KwapongCiccarone Center for the Prevention of Cardiovascular Diseases Johns Hopkins University Baltimore MD USA.
Theresa BoyerDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0002-8071-9351
Oluwalonimi AdebowaleJohns Hopkins Bayview Medical Center Baltimore MD USA.ORCID 0009-0008-7122-0824
S Michelle OgunwoleDivision of General Internal Medicine Johns Hopkins University School of Medicine Baltimore MD USA.ORCID 0000-0001-9479-7695
Arthur Jason VaughtDivision of Maternal Fetal Medicine, Department of Gynecology and Obstetrics Johns Hopkins University Baltimore MD USA.ORCID 0000-0002-2370-3716
Chiadi E NdumeleCiccarone Center for the Prevention of Cardiovascular Diseases Johns Hopkins University Baltimore MD USA.ORCID 0000-0002-1603-282X
Allison G HaysCiccarone Center for the Prevention of Cardiovascular Diseases Johns Hopkins University Baltimore MD USA.ORCID 0000-0003-2138-1589
Roger S BlumenthalCiccarone Center for the Prevention of Cardiovascular Diseases Johns Hopkins University Baltimore MD USA.ORCID 0000-0003-1910-3168
Erin D MichosCiccarone Center for the Prevention of Cardiovascular Diseases Johns Hopkins University Baltimore MD USA.ORCID 0000-0002-5547-5084
Elizabeth SelvinDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0002-3539-2070
Josef CoreshDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0002-4598-0669
Anum S MinhasCiccarone Center for the Prevention of Cardiovascular Diseases Johns Hopkins University Baltimore MD USA.ORCID 0000-0001-6680-0404

Funding

CARDIOVASCULAR EPIDEMIOLOGY INSTITUTIONAL TRAININGT32HL007024 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Elizabeth Selvin · 1985 to 2026
$17.5M
Institutional Career Development CoreKL2TR003099 · NCATS · JOHNS HOPKINS UNIVERSITY · PI GEBO, KELLY A · 2019 to 2023
$7.9M
Research and Mentoring in the Clinical Epidemiology of Cardiovascular Disease and Type 2 DiabetesK24HL152440 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SELVIN, ELIZABETH · 2020 to 2024
$612k
Intersections of pre-pregnancy cardiometabolic risk factors, preeclampsia and cardiovascular disease in a lifecourse frameworkK23HL171886 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Anum Minhas · 2024 to 2026
$603k
NCATS NIH HHS KL2 TR003099NHLBI NIH HHS K23 HL171886NHLBI NIH HHS K24 HL152440NHLBI NIH HHS T32 HL007024
6 · The paper itself

Abstract

backgroundPrepregnancy diabetes and obesity are associated with hypertensive disorders of pregnancy (HDPs). However, the proportion of cases of HDP in the population explained by diabetes and obesity (population attributable fraction), especially among American Indian and Alaska Native and Native Hawaiian and Other Pacific Islander, is not well characterized. METHODS AND

resultsWe conducted a cross-sectional analysis of data on individuals with a live singleton birth from the US National Vital Statistics System between 2016 and 2019. We used adjusted logistic regression to estimate the prevalence odds ratios of HDPs and tested interaction for race and ethnicity. We calculated the population attributable fraction for the effect of obesity and diabetes on HDPs. Among 13 201 338 birthing individuals, (mean age, 29±6 years), 7% had HDP. The prevalence of HDP was highest among American Indian and Alaska Native individuals (9.1%). Prepregnancy diabetes (prevalence odds ratio, 2.63 [95% CI, 2.59-2.67]) and obesity (prevalence odds ratio, 2.95 [95% CI, 2.93-2.97]) were associated with HDPs. Compared with non-Hispanic White individuals, the association of diabetes with HDPs was strongest among Native Hawaiian and Other Pacific Islander (prevalence odds ratio, 3.05 [95% CI, 2.48-3.77]), and the association of obesity with HDP was strongest among Asian individuals (prevalence odds ratio, 3.44 [95% CI, 3.35-3.54]; all

conclusionsPrepregnancy diabetes and obesity are associated with HDP across all racial and ethnic groups. Diabetes and obesity have highest population attributable fractions among Native Hawaiian and Other Pacific Islander individuals and should be aggressively targeted during childhood, adolescence, and young adulthood to reduce risk of HDPs.

Indexed as

Hypertension, Pregnancy-InducedObesityAdultAmerican Indian or Alaska NativeCross-Sectional StudiesDiabetes MellitusFemaleHumansNative Hawaiian or Pacific IslanderPregnancyPrevalenceRisk FactorsUnited StatesYoung Adultcardiometabolic healthdisparitieshypertensive disorders of pregnancynativityrace and ethnicity

Identifiers

PMID39424428
PMCPMC11935733

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.