Evidence map›Paper›PMID 39424401›Full record

ArticleJournal of the American Heart Association2024

Correlation and Agreement of Quantitative Flow Ratio With Fractional Flow Reserve in Saphenous Vein Grafts.

Ruben W de Winter, Yvemarie B O Somsen, Roel Hoek, Pepijn A van Diemen, Ruurt A Jukema, Mathé P Jonker, Albert C van Rossum, Jos W R Twisk, Rolf A Kooistra, Jasper Janssen and 7 more

Abstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Comparison of Fractional Flow Reserve and Myocardial Perfusion Imaging in Saphenous Vein Grafts.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ruben W de WinterDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0003-2199-5943
Yvemarie B O SomsenDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0009-0002-2585-9631
Roel HoekDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0002-7927-0366
Pepijn A van DiemenDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Ruurt A JukemaDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0002-3212-2665
Mathé P JonkerDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Albert C van RossumDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0003-1714-4652
Jos W R TwiskDepartment of Epidemiology & Data Science Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Rolf A KooistraMedis Medical Imaging Leiden The Netherlands.
Jasper JanssenMedis Medical Imaging Leiden The Netherlands.
Sina PorouchaniDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0001-9357-8773
Adriaan WilgenhofDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0002-3263-7394
Niels J VeroudenDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Ibrahim DanadDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Johan H C ReiberMedis Medical Imaging Leiden The Netherlands.ORCID 0000-0002-0387-6417
Alexander NapDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0001-9184-3561
Paul KnaapenDepartment of Cardiology Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0001-8038-7898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe applicability of quantitative flow ratio (QFR), a nonhyperemic, invasive coronary angiography-derived computation of fractional flow reserve (FFR), has not been studied in coronary artery bypass grafts. We sought to explore the correlation and diagnostic agreement between QFR and FFR in saphenous vein grafts (SVGs). METHODS AND

resultsA total of 129 prospectively included patients (mean age 73±8 years, 84% male) with prior coronary artery bypass grafting underwent invasive coronary angiography and pressure-derived functional assessment in 150 nonoccluded SVGs. QFR dedicated angiography images of the SVGs were acquired and used for offline QFR computation. The diagnostic performance of QFR was compared with 2-dimensional quantitative coronary angiography, using FFR as a reference. A threshold of ≤0.80 was used to define functional significance. QFR was successfully computed in 140 (93%) SVGs. We found a significant correlation between QFR and FFR (r=0.72,

conclusionsThis study shows the potential applicability of contemporary QFR computation in venous bypass grafts with a moderate correlation and good diagnostic accuracy compared with functional assessment using FFR.

Indexed as

Coronary AngiographyCoronary Artery BypassFractional Flow Reserve, MyocardialSaphenous VeinAgedAged, 80 and overCardiac CatheterizationCoronary Artery DiseaseFemaleGraft Occlusion, VascularHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesReproducibility of Resultsfractional flow reservequantitative flow ratiosaphenous vein grafts

Identifiers

PMID39424401
PMCPMC11935732

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.