SynthesisJournal of neurointerventional surgery2025
Transcranial doppler (TCD) in predicting outcomes following successful mechanical thrombectomy of large vessel occlusions in anterior circulation: a systematic review and meta-analysis.
Synthesis in Journal of neurointerventional surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Microembolic signals in transcranial Doppler and the functional outcome of patients with acute ischemic stroke: a meta-analysis.Frontiers in neurology · 2026Pooled it
- Prognostic Value of Cerebral Hemodynamics Assessment on 24-h Transcranial Color-Coded Doppler Following a Successful Thrombectomy.European journal of neurology · 2025Observational
- Risk Prediction of Cerebrovascular Ischemic Events Following Cervical Artery Dissections Using High-Intensity Transient Signals: A Systematic Review, Meta-Analysis and a single center experience.Stroke (Hoboken, N.J.) · 2025Article
- No impact of intravenous thrombolysis on post thrombectomy transcranial Doppler pulsatility index.Frontiers in neurology · 2025Article
- Outcomes with General Anesthesia Compared to Conscious Sedation for Endovascular Treatment of Medium Vessel Occlusions: Results of an International Multicentric Study.Clinical neuroradiology · 2024Article
- Association of Early M2 Pulsatility Index Ratio With Outcomes After Successful Endovascular Thrombectomy.Journal of neuroimaging : official journal of the American Society of NeuroimagingArticle
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Authors and funding
12 authors.
Funding
Abstract
backgroundTranscranial Doppler (TCD) is a non-invasive, bedside tool that allows for real-time monitoring of the patient's hemodynamic status following mechanical thrombectomy (MT). This systematic review and meta-analysis aims to evaluate the predictive value of TCD parameters following successful MT (Thrombolysis in Cerebral Infarction 2b-3).
methodsIn July 2024, we searched PubMed, Embase, and Scopus, to identify observational studies in which TCD parameters were measured within 48 hours of MT. Using random-effects models, we compared four TCD parameters (mean flow velocity (MFV), MFV index, pulsatility index (PI), and peak systolic velocity (PSV) among groups with vs without hemorrhagic transformation (HT) and favorable vs poor functional recovery (modified Rankin Scale 0-2 vs 3-6).
resultsEleven studies comprising 1432 patients (59% male; mean age range: 63-73 years) were included. The MFV and MFV index were higher in patients with HT (Hedges' g=0.42 and 0.54, P=0.015 and 0.005, respectively). Patients with MFV index ≥1.3 showed a higher risk of all HT (RR 1.97; 95% confidence interval (CI) 1.28 to 3.03, P=0.002), symptomatic HT (RR 4.68; 95% CI 1.49 to 14.65, P=0.008), and poor functional status at 90 days (RR 1.65; 95% CI 1.27 to 2.14, P=0.029), respectively. There was no difference in mean PSV (P=0.1) and PI (P=0.3) among groups with and without HT.
conclusionThis study underscores the prognostic value of the MFV index in predicting HT, symptomatic HT, and poor functional recovery after successful MT in the anterior circulation. Large-scale, multi-center studies are necessary to confirm these findings and to validate the MFV index as a reliable predictor for improving post-thrombectomy care.
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