Evidence map›Paper›PMID 39422490›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2025

Extending insights from LeDoux: using movies to study subjective, clinically meaningful experiences in neuroscience.

Peter A Kirk, Daniel S Pine, Katharina Kircanski

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Peter A KirkEmotion and Development Branch, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, United States.ORCID 0000-0003-0786-3039
Daniel S PineEmotion and Development Branch, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, United States.ORCID 0000-0002-4301-9516
Katharina KircanskiEmotion and Development Branch, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, United States.ORCID 0000-0002-6546-5584

Funding

fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
Intramural NIH HHS ZIA MH002781NIH HHS ZIAMH002781
6 · The paper itself

Abstract

Neuroscience research with public health relevance to emotional disorders examines brain-behavior relations. Joe LeDoux's legacy advances these efforts in ways that remain truly unique. While recognized for his basic science research, he also inspires applied researchers, guiding an agenda for clinical scientists: understanding the pathophysiology of altered subjective experiences in emotional disorders. For brain imaging, movie-watching approaches help clinicians realize this agenda due to movies' relative strength in evoking rich, meaningful subjective experiences. Here, we describe methodological advances in movie-watching paradigms that might sustain LeDoux's impact by facilitating the discovery of neural mechanisms generating complex emotional responses. Of note, while linking subjective emotion to pathophysiology is a first step, innovations in movie-watching designs, especially involving therapeutic techniques for emotional disorders, can boost clinical application. Leveraging research on pathophysiology to generate novel therapy reflects the clinical legacy sustained through Joe LeDoux's rousing career.

Indexed as

EmotionsMotion PicturesNeurosciencesBrainHumansanxietyfearmovie-watchingnaturalisticpsychiatry

Identifiers

PMID39422490
PMCPMC11712263

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.