Evidence map›Paper›PMID 39422243›Full record

ReviewJournal of leukocyte biology2024

The peripheral neuroimmune system.

Keaton Song, Brian S Kim

Abstract readReview
In one paragraph

Review in Journal of leukocyte biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. The neuroimmune system and cognition.Nature immunology · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Keaton SongGraduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA.
Brian S KimFriedman Brain Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA.ORCID 0009-0009-9546-4273

Funding

Neuroimmune Regulation of Atopic DermatitisR01AR070116 · NIAMS · WASHINGTON UNIVERSITY · PI KIM, BRIAN · 2016 to 2021
$3.8M
Regulation of IgE and Atopic ItchR01AI167933 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CONROY, MICHELLE E, KIM, BRIAN · 2022 to 2025
$3.2M
Developing an Objective and Quantifiable Measure of Itch Using Artificial Intelligence and Radio SignalsR01AR080392 · NIAMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI KATABI, DINA · 2022 to 2024
$642k
The Role of IL-33 in Chronic ItchR21AI167047 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KIM, BRIAN · 2021 to 2022
$460k
Allen Discovery Center programNational Institute of Allergy and Infectious Disease AI167933NIAID NIH HHS R21 AI167047NIAMS NIH HHS AR070116NIAMS NIH HHS R01 AR080392NIH HHSPaul G. Allen Family FoundationPaul G. Allen Frontiers Group advised program
6 · The paper itself

Abstract

Historically, the nervous and immune systems were studied as separate entities. The nervous system relays signals between the body and the brain by processing sensory inputs and executing motor outputs, whereas the immune system provides protection against injury and infection through inflammation. However, recent developments have demonstrated that these systems mount tightly integrated responses. In particular, the peripheral nervous system acts in concert with the immune system to control reflexes that maintain and restore homeostasis. Notwithstanding their homeostatic mechanisms, dysregulation of these neuroimmune interactions may underlie various pathological conditions. Understanding how these two distinct systems communicate is an emerging field of peripheral neuroimmunology that promises to reveal new insights into tissue physiology and identify novel targets to treat disease.

Indexed as

NeuroimmunomodulationPeripheral Nervous SystemAnimalsHomeostasisHumansImmune Systemitch biologymast cellneuroimmunologyneuropeptidesensory biology

Identifiers

PMID39422243
PMCPMC11599120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.