Evidence map›Paper›PMID 39421910›Full record

Trial reportEarly intervention in psychiatry2025

Feasibility and Acceptability of Providing Cognitive Remediation in a Large USA System of Coordinated Specialty Care for Early Psychosis.

Alice Medalia, Alice M Saperstein, Melanie M Wall, Cale N Basaraba, Iruma Bello, Ilana Nossel, Lisa B Dixon

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alice MedaliaNew York State Psychiatric Institute, Department of Psychiatry, Columbia University Vagelos College of Physicians & Surgeons, and New York-Presbyterian, New York, New York, USA.
Alice M SapersteinNew York State Psychiatric Institute, Department of Psychiatry, Columbia University Vagelos College of Physicians & Surgeons, and New York-Presbyterian, New York, New York, USA.ORCID 0000-0001-7844-4371
Melanie M WallNew York State Psychiatric Institute and Department of Psychiatry, Columbia University Vagelos College of Physicians & Surgeons, New York, New York, USA.
Cale N BasarabaNew York State Psychiatric Institute and Department of Psychiatry, Columbia University Vagelos College of Physicians & Surgeons, New York, New York, USA.
Iruma BelloNew York State Psychiatric Institute and Department of Psychiatry, Columbia University Vagelos College of Physicians & Surgeons, New York, New York, USA.
Ilana NosselNew York State Psychiatric Institute and Department of Psychiatry, Columbia University Vagelos College of Physicians & Surgeons, New York, New York, USA.
Lisa B DixonNew York State Psychiatric Institute and Department of Psychiatry, Columbia University Vagelos College of Physicians & Surgeons, New York, New York, USA.

Funding

Does the Addition of Cognitive Remediation to Coordinated Specialty Care Services Improve Functional Outcome?R34MH118318 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MEDALIA, ALICE · 2019 to 2022
$724k
NIMH NIH HHS R34 MH118318NIMH NIH HHS R34MH118318
6 · The paper itself

Abstract

introductionMultinational treatment guidelines support providing cognitive remediation to people recently diagnosed with schizophrenia, but the feasibility of implementing the treatment on a large scale is less well understood.

methodsThis study took place between 2019 and 2023 at 14 clinics within a large network of programs providing early intervention services to people aged 16-30 experiencing nonaffective psychosis. Clinics were randomly assigned to deliver cognitive remediation as twice-weekly clinician-led groups (N = 5), cognitive remediation as once-weekly clinician-led groups with homework (N = 6), or treatment as usual (N = 3). All clinics screened for cognitive health need to guide treatment planning. Clinical teams (N = 11) received training to provide cognitive remediation. Program evaluation data were analysed for feasibility and acceptability.

resultsScreening for cognitive health needs was completed on 77% of the 1193 participants enrolled at the 11 clinics offering cognitive remediation. Clinicians identified cognitive difficulties in 53.9% (n = 496) of screened participants and referred 27% (n = 134) of these participants to cognitive remediation. Of referred participants, 77.6% (n = 104) initiated treatment, and n = 41 completed the treatment. The rate of referral was nearly double, and treatment initiation was significantly higher at programs delivering once-weekly (84.3%) than twice-weekly (64.4%) treatment but the difference in the rate of treatment completion was statistically nonsignificant. Satisfaction among treatment completers was high.

conclusionsReferrals to cognitive remediation required systemic support of a feasible cognitive health screening process. About a quarter of people with clinician-identified cognitive health needs were referred to cognitive remediation. Feasibility data suggest a flexible model of treatment delivery may facilitate implementation in this service setting.

Indexed as

Cognitive RemediationEarly Medical InterventionPatient Acceptance of Health CarePsychotic DisordersSchizophreniaAdolescentAdultFeasibility StudiesFemaleHumansMaleUnited StatesYoung Adultcognitioncognitive healthcognitive remediationcoordinated speciality careearly psychosis

Identifiers

PMID39421910
PMCPMC11732730

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.