Evidence map›Paper›PMID 39421828›Full record

ArticleFrontiers in veterinary science2024

Therapeutic effects of myrrh extract and myrrh-based silver nanoparticles on

Salwa Mahmoud Abd-ELrahman, Ahmed Kamal Dyab, Abeer El-Sayed Mahmoud, Shaymaa M Mohamed, Alamira Marzouk Fouad, Ahmed Gareh, Jamal Asseri, Naief Dahran, Hind Alzaylaee, Hayat M Albisihi and 6 more

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Frontiers in veterinary science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Salwa Mahmoud Abd-ELrahmanDepartment of Parasitology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
Ahmed Kamal DyabDepartment of Medical Parasitology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Abeer El-Sayed MahmoudDepartment of Medical Parasitology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Shaymaa M MohamedDepartment of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Alamira Marzouk FouadDepartment of Aquatic Animal Medicine and Management, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
Ahmed GarehDepartment of Parasitology, Faculty of Veterinary Medicine, Aswan University, Aswan, Egypt.
Jamal AsseriDepartment of Biology, College of Science and Humanities, Shaqra University, Dawadmi, Saudi Arabia.
Naief DahranDepartment of Anatomy, Faculty of Medicine, University of Jeddah, Jeddah, Saudi Arabia.
Hind AlzaylaeeDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Hayat M AlbisihiDepartment of Biochemistry, College of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
Ahmed Mahmoud Abd ElrahmanDepartment of Chemistry, Faculty of Science, Assiut University, Asyut, Egypt.
Fahd M AlsharifDepartment of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Al-Azhar University, Assiut, Egypt.
Heba MostafaDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
Nashwa HamadDepartment of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
Ehab Kotb ElmahallawyDepartamento de Sanidad Animal, Grupo de Investigación en Sanidad Animal y Zoonosis (GISAZ), UIC Zoonosis y Enfermedades Emergentes ENZOEM, Universidad de Córdoba, Córdoba, Spain.
Nahed Ahmed ElossilyDepartment of Medical Parasitology, Faculty of Medicine, Assiut University, Assiut, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Trichinellosis, caused by Methods: This study evaluated the effects of silver nanoparticles biosynthesized using myrrh, crude myrrh extracts, and albendazole on the intestinal phase of Results: The present study showed a considerable reduction in adult worm count among the treated groups. The mortality rates of adult worms were 88.64% in the silver nanoparticles treated group, 85.17% in the myrrh crude extract group, and 94.07% in the albendazole-treated group. Histopathological examination revealed prominent alterations in the intestine of the infected non-treated mice, which were markedly restored by treatment. Immunohistochemical examination accompanied by significant reduction in MMP-9 expression in the infected mice treated with AgNPs compared to the infected non-treated group, reflecting the role of AgNPs in downgrading the inflammatory reaction in the intestine of infected mice. Conclusion: Collectively, this study demonstrates the novel antiparasitic potential of silver nanoparticles biosynthesized with myrrh against

Indexed as

anthelminticcytokinehistopathologyimmunologymyrrhsilver nanoparticlesTrichinella

Identifiers

PMID39421828
PMCPMC11483346

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.