Evidence map›Paper›PMID 39421629›Full record

ReviewSovremennye tekhnologii v meditsine2024

Neurogenetics of Brain Connectivity: Current Approaches to the Study (Review).

E A Proshina, T S Deynekina, O V Martynova

Abstract readReview
In one paragraph

Review in Sovremennye tekhnologii v meditsine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

E A ProshinaResearcher, Centre for Cognition & Decision Making, Institute for Cognitive Neurosciences; National Research University Higher School of Economics, 20 Myasnitskaya St., Moscow, 101000, Russia.
T S DeynekinaAnalyst; Center for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, 10 Pogodinskaya St., Moscow, 119121, Russia.
O V MartynovaDeputy Director, Head of the Laboratory of Human Higher Nervous Activity; Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, 5A Butlerova St., Moscow, 117485, Russia, Associate Professor, Department of Biology and Biotechnology; National Research University Higher School of Economics, 20 Myasnitskaya St., Moscow, 101000, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to the advances of neuroimaging techniques, a number of functional brain networks associated both with specific functions and the state of relative inactivity has been distinguished. A sufficient bulk of information has been accumulated on changes in connectivity (links between brain regions) in psychopathologies, for example, depression, schizophrenia, autism. Their genetic markers are being actively investigated using a candidate-gene approach or a genome-wide association study. At the same time, there is not much data considering connectivity as an intermediate link in the genotype-pathology chain, although it seems to be a reliable endophenotype, since it demonstrates a high stability and high heritability. In the present review, we consider the results of investigations devoted to the search for biomarkers, molecular and genetic associations of functional, partially anatomical, and effective connectivity. The main approaches to the evaluation of connectivity neurogenetics have been described, as well as specific genetic variants, for which the association with brain connectivity in psychiatric pathologies has been detected.

Indexed as

BrainGenome-Wide Association StudyHumansMental DisordersNeuroimagingconnectivityEEGfMRIgenome-wide association studyheritabilityneural networkneurogenetics

Identifiers

PMID39421629
PMCPMC11482091

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.